Improving timing resolution of BGO for TOF-PET: a comparative analysis with and without deep learning

[Background] The renewed interest in BGO scintillators for TOF-PET is driven by the improved Cherenkov photon detection with new blue-sensitive SiPMs. However, the slower scintillation light from BGO causes significant time walk with leading edge discrimination (LED), which degrades the coincidence...

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Detalles Bibliográficos
Autores: Loignon-Houle, Francis, Kratochwil, Nicolaus, Toussaint, Maxime, Lowis, Carsten, Ariño-Estrada, Gerard, Gonzalez, Antonio J., Auffray, Etiennette, Lecomte, Roger
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/394566
Acceso en línea:http://hdl.handle.net/10261/394566
https://api.elsevier.com/content/abstract/scopus_id/85218252837
Access Level:acceso abierto
Palabra clave:BGO
Cherenkov
Deep learning
Fast timing
Time resolution
Time-of-flight PET
Descripción
Sumario:[Background] The renewed interest in BGO scintillators for TOF-PET is driven by the improved Cherenkov photon detection with new blue-sensitive SiPMs. However, the slower scintillation light from BGO causes significant time walk with leading edge discrimination (LED), which degrades the coincidence time resolution (CTR). To address this, a time walk correction (TWC) can be done by using the rise time measured with a second threshold. Deep learning, particularly convolutional neural networks (CNNs), can also enhance CTR by training with digitized waveforms. It remains to be explored how timing estimation methods utilizing one (LED), two (TWC), or multiple (CNN) waveform data points compare in CTR performance of BGO scintillators.