Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into cancer and Nutrition

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Inve...

Full description

Bibliographic Details
Authors: Obón Santacana, Mireia, Luján Barroso, Leila, Freisling, Heinz, Naudin, Sabine, Boutron-Ruault, Marie-Christine, Mancini, Francesca Romana, Rebours, Vinciane, Kühn, Tilman, Katzke, Verena, Boeing, Heiner, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Lasheras, Cristina, Rodríguez Barranco, Miguel, Amiano, Pilar, Santiuste, Carmen, Ardanaz, Eva, Khaw, Kay-Thee, Wareham, Nicholas J., Schmidt, Julie A., Aune, Dagfinn, Trichopoulou, Antonia, Thriskos, Paschalis, Peppa, Eleni, Masala, Giovanna, Grioni, Sara, Tumino, Rosario, Panico, Salvatore, Bueno de Mesquita, H. Bas, Sciannameo, Veronica, Vermeulen, Roel, Sonestedt, Emily, Sund, Mali, Weiderpass, Elisabete, Skeie, Guri, González, Carlos A., Riboli, Elio, Duell, Eric J.
Format: article
Status:Versión aceptada para publicación
Publication Date:2019
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/173527
Online Access:https://hdl.handle.net/2445/173527
Access Level:Open access
Keyword:Càncer
Nutrició
Cuina (Nous)
Llavors
Cancer
Nutrition
Cooking (Nuts)
Seeds
Description
Summary:Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country‐specific dietary questionnaires. After a mean follow‐up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p‐trend = 0.70). Furthermore, no evidence for effect‐measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.

Similar Items