Palladium-Catalyzed Oxidative Arene C-H Alkenylation Reactions Involving Olefins

The Palladium-catalyzed selective C-H alkenylation reaction has been established as a central synthetic transformation to enable the construction of carbon–carbon bonds in an efficient, atom-economical, and environmentally friendly way. It provides a powerful alternative to classical cross-coupling...

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Detalhes bibliográficos
Autores: Carral Menoyo, Asier, Sotomayor Anduiza, María Nuria, Lete Expósito, María Esther
Tipo de documento: artigo
Data de publicação:2022
País:España
Recursos:Universidad del País Vasco
Repositório:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/63177
Acesso em linha:http://hdl.handle.net/10810/63177
Access Level:Acceso aberto
Palavra-chave:palladium
C-H activation
alkenylation
catalysis
Descrição
Resumo:The Palladium-catalyzed selective C-H alkenylation reaction has been established as a central synthetic transformation to enable the construction of carbon–carbon bonds in an efficient, atom-economical, and environmentally friendly way. It provides a powerful alternative to classical cross-coupling reactions for the construction of conjugated organic molecules, including late-stage functionalization. The knowledge of mechanisms, the use of different strategies to control site-selectivity, and the development of efficient chiral catalysts for C-H alkenylation reactions has expanded the application of this tool for the synthesis of molecules of increased complexity