Iridium‐Catalyzed β‐Alkynylation of Aliphatic Oximes as Masked Carbonyl Compounds and Alcohols

An Ir‐catalyzed C(sp3)−H alkynylation of aliphatic ketones, aldehydes, and alcohols was achieved by using the corresponding oxime derivatives and a IrIII catalyst. This general reaction is selective towards primary C(sp3)−H bonds and can be used for the late‐stage C−H alkynylation of complex molecul...

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Detalles Bibliográficos
Autores: Tan, Eric, Zanini, Margherita, Echavarren, Antonio M.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/447786
Acceso en línea:http://hdl.handle.net/2072/447786
https://doi.org/10.1002/anie.202002948
Access Level:acceso abierto
Palabra clave:54
Descripción
Sumario:An Ir‐catalyzed C(sp3)−H alkynylation of aliphatic ketones, aldehydes, and alcohols was achieved by using the corresponding oxime derivatives and a IrIII catalyst. This general reaction is selective towards primary C(sp3)−H bonds and can be used for the late‐stage C−H alkynylation of complex molecules.