Periprandial changes in brain serotonergic system and food intake related neuropeptides [Dataset]

In this work, we assessed periprandial serotonin and 5-hydroxyindolacetic acid abundance in several brain areas of rainbow trout, in parallel with the evaluation of gene expression of tryptophan hydroxilase 1 and 2, neuropeptides involved in the central control of food intake, and the quantification...

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Detalles Bibliográficos
Autores: Chivite, Mauro, Míguez, Jesús M., Ceinos, Rosa M., López-Patiño, Marcos A., Cerdá-Reverter, José Miguel, Soengas, José L., Aldegunde, Manuel
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/349280
Acceso en línea:http://hdl.handle.net/10261/349280
Access Level:acceso abierto
Palabra clave:Serotonin
Trout
Biological sciences
Food intake
HPLC
Descripción
Sumario:In this work, we assessed periprandial serotonin and 5-hydroxyindolacetic acid abundance in several brain areas of rainbow trout, in parallel with the evaluation of gene expression of tryptophan hydroxilase 1 and 2, neuropeptides involved in the central control of food intake, and the quantification of plasma glucose and cortisol. The results showed severe changes in serotonergic systems around mealtime, the most prominent being the increase in their activity just after food intake, suggesting that serotonin has a relevant role in relation to the daily timing of food intake, probably triggering satiety signals. In addition, a temporal adjustment of neuropeptide expression and plasma cortisol was found in relation to food intake, supporting its role in the regulation of feeding behaviour.