EEG markers and subjective memory complaints in young and older people

Subjective memory complaints (SMCs) have been related to subtle cognitive deficits and neural changes. In this study, we investigated whether EEG rhythms, usually altered in mild cognitive impairment and Alzheimer's disease, are also affected in SMCs compared to people without SMCs. Seventy-one...

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Detalhes bibliográficos
Autores: Perez, Vanesa, Garrido-Chaves, Ruth, Zapater-Fajarí, Mariola, Pulopulos, Matias M., Hidalgo, Vanesa, Salvador, Alicia
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:120034
Acesso em linha:http://zaguan.unizar.es/record/120034
Access Level:acceso abierto
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spelling EEG markers and subjective memory complaints in young and older peoplePerez, VanesaGarrido-Chaves, RuthZapater-Fajarí, MariolaPulopulos, Matias M.Hidalgo, VanesaSalvador, AliciaSubjective memory complaints (SMCs) have been related to subtle cognitive deficits and neural changes. In this study, we investigated whether EEG rhythms, usually altered in mild cognitive impairment and Alzheimer's disease, are also affected in SMCs compared to people without SMCs. Seventy-one older adults (55–74 years old) and 75 young people (18–34 years old) underwent 3 min of EEG recording in a resting-state condition with their eyes open (EO) and eyes closed (EC) and a comprehensive neuropsychological evaluation. The EEG measures included were power spectral delta (0.5–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), beta (13–30 Hz), and EEG reactivity to EO. Compared to controls, older people with SMCs showed increased theta power and a loss of alpha reactivity to EO. Additionally, in older participants with SMCs, the theta power spectral was related to deficits in verbal memory. In contrast, we failed to find differences in the young people with SMCs, compared to the control group, in the power spectral or the EEG reactivity to EO. Our findings suggest that neurophysiological markers of brain dysfunction may identify cognitive changes even before they are observed on objective neuropsychological tests, at least in older people.2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/120034reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/grantAgreement/ES/DGA/S31-20Dinfo:eu-repo/grantAgreement/ES/MCIU/FPU17-03428info:eu-repo/grantAgreement/ES/MICIU/PID2020-119406GB-I00info:eu-repo/semantics/openAccessoai:zaguan.unizar.es:1200342026-05-29T13:59:51Z
dc.title.none.fl_str_mv EEG markers and subjective memory complaints in young and older people
title EEG markers and subjective memory complaints in young and older people
spellingShingle EEG markers and subjective memory complaints in young and older people
Perez, Vanesa
title_short EEG markers and subjective memory complaints in young and older people
title_full EEG markers and subjective memory complaints in young and older people
title_fullStr EEG markers and subjective memory complaints in young and older people
title_full_unstemmed EEG markers and subjective memory complaints in young and older people
title_sort EEG markers and subjective memory complaints in young and older people
dc.creator.none.fl_str_mv Perez, Vanesa
Garrido-Chaves, Ruth
Zapater-Fajarí, Mariola
Pulopulos, Matias M.
Hidalgo, Vanesa
Salvador, Alicia
author Perez, Vanesa
author_facet Perez, Vanesa
Garrido-Chaves, Ruth
Zapater-Fajarí, Mariola
Pulopulos, Matias M.
Hidalgo, Vanesa
Salvador, Alicia
author_role author
author2 Garrido-Chaves, Ruth
Zapater-Fajarí, Mariola
Pulopulos, Matias M.
Hidalgo, Vanesa
Salvador, Alicia
author2_role author
author
author
author
author
description Subjective memory complaints (SMCs) have been related to subtle cognitive deficits and neural changes. In this study, we investigated whether EEG rhythms, usually altered in mild cognitive impairment and Alzheimer's disease, are also affected in SMCs compared to people without SMCs. Seventy-one older adults (55–74 years old) and 75 young people (18–34 years old) underwent 3 min of EEG recording in a resting-state condition with their eyes open (EO) and eyes closed (EC) and a comprehensive neuropsychological evaluation. The EEG measures included were power spectral delta (0.5–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), beta (13–30 Hz), and EEG reactivity to EO. Compared to controls, older people with SMCs showed increased theta power and a loss of alpha reactivity to EO. Additionally, in older participants with SMCs, the theta power spectral was related to deficits in verbal memory. In contrast, we failed to find differences in the young people with SMCs, compared to the control group, in the power spectral or the EEG reactivity to EO. Our findings suggest that neurophysiological markers of brain dysfunction may identify cognitive changes even before they are observed on objective neuropsychological tests, at least in older people.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://zaguan.unizar.es/record/120034
url http://zaguan.unizar.es/record/120034
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/ES/DGA/S31-20D
info:eu-repo/grantAgreement/ES/MCIU/FPU17-03428
info:eu-repo/grantAgreement/ES/MICIU/PID2020-119406GB-I00
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv
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dc.source.none.fl_str_mv reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname:Universidad de Zaragoza
instname_str Universidad de Zaragoza
reponame_str Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection Zaguán. Repositorio Digital de la Universidad de Zaragoza
repository.name.fl_str_mv
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