Generation of Individualized Synthetic Data for Augmentation of the Type 1 Diabetes Data Sets Using Deep Learning Models

In this paper, we present a methodology based on generative adversarial network architecture to generate synthetic data sets with the intention of augmenting continuous glucose monitor data from individual patients. We use these synthetic data with the aim of improving the overall performance of pre...

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Detalles Bibliográficos
Autores: Noguer, Josep, Contreras, Ivan, Mujahid, Omer, Beneyto Tantiña, Aleix, Vehí, Josep
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/21277
Acceso en línea:http://hdl.handle.net/10256/21277
Access Level:acceso abierto
Palabra clave:Monitoratge de pacients
Patient monitoring
Diabetis
Diabetes
Aprenentatge automàtic
Machine learning
Intel·ligència artificial -- Aplicacions a la medicina
Artificial intelligence -- Medical applications
Glucèmia -- Control automàtic
Blood sugar -- Automatic control
Descripción
Sumario:In this paper, we present a methodology based on generative adversarial network architecture to generate synthetic data sets with the intention of augmenting continuous glucose monitor data from individual patients. We use these synthetic data with the aim of improving the overall performance of prediction models based on machine learning techniques. Experiments were performed on two cohorts of patients suffering from type 1 diabetes mellitus with significant differences in their clinical outcomes. In the first contribution, we have demonstrated that the chosen methodology is able to replicate the intrinsic characteristics of individual patients following the statistical distributions of the original data. Next, a second contribution demonstrates the potential of synthetic data to improve the performance of machine learning approaches by testing and comparing different prediction models for the problem of predicting nocturnal hypoglycemic events in type 1 diabetic patients. The results obtained for both generative and predictive models are quite encouraging and set a precedent in the use of generative techniques to train new machine learning models