Thermomechanical Transitions of Egg-Ceramide Monolayers

Ceramides have unique biophysical properties. Their high melting temperature and their ability to form lateral domains have converted ceramides into the paradigm of rigid lipids. Here, using shear surface rheology of egg-ceramide Langmuir monolayers, a solid to fluid transition was evidenced as a va...

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Detalles Bibliográficos
Autores: Catapano, Elisa R., Lillo, M. P., García Rodríguez, C., Natale, Paolo, Langevin, D., Monroy Muñoz, Francisco, López-Montero, Iván
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/34193
Acceso en línea:https://hdl.handle.net/20.500.14352/34193
Access Level:acceso abierto
Palabra clave:Lipids
Monolayers
Compression
Fluids
Phase transitions
Química física (Química)
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spelling Thermomechanical Transitions of Egg-Ceramide MonolayersCatapano, Elisa R.Lillo, M. P.García Rodríguez, C.Natale, PaoloLangevin, D.Monroy Muñoz, FranciscoLópez-Montero, IvánLipidsMonolayersCompressionFluidsPhase transitionsQuímica física (Química)Ceramides have unique biophysical properties. Their high melting temperature and their ability to form lateral domains have converted ceramides into the paradigm of rigid lipids. Here, using shear surface rheology of egg-ceramide Langmuir monolayers, a solid to fluid transition was evidenced as a vanishing shear rigidity at lower temperatures than the lipid melting temperature. Such a mechanical transition, which depends on the lipid lateral pressure, was found in a broad range temperature (40−50 °C). The solid to fluid transition was correlated to a LC to LC+LE phase transition, as confirmed by BAM experiments. Interestingly, together with the softening transition, a supercooling process compatible with a glassy behavior was found upon freezing. A new phase scenario is then depicted that broadens the mechanical behavior of natural ceramides. The phase diversity of ceramides might have important implications in their physiological roles.American Chemical SocietyUniversidad Complutense de Madrid20152015-01-0120152015-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/34193reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial-SinDerivadas 3.0 Españahttps://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/341932026-06-02T12:44:21Z
dc.title.none.fl_str_mv Thermomechanical Transitions of Egg-Ceramide Monolayers
title Thermomechanical Transitions of Egg-Ceramide Monolayers
spellingShingle Thermomechanical Transitions of Egg-Ceramide Monolayers
Catapano, Elisa R.
Lipids
Monolayers
Compression
Fluids
Phase transitions
Química física (Química)
title_short Thermomechanical Transitions of Egg-Ceramide Monolayers
title_full Thermomechanical Transitions of Egg-Ceramide Monolayers
title_fullStr Thermomechanical Transitions of Egg-Ceramide Monolayers
title_full_unstemmed Thermomechanical Transitions of Egg-Ceramide Monolayers
title_sort Thermomechanical Transitions of Egg-Ceramide Monolayers
dc.creator.none.fl_str_mv Catapano, Elisa R.
Lillo, M. P.
García Rodríguez, C.
Natale, Paolo
Langevin, D.
Monroy Muñoz, Francisco
López-Montero, Iván
author Catapano, Elisa R.
author_facet Catapano, Elisa R.
Lillo, M. P.
García Rodríguez, C.
Natale, Paolo
Langevin, D.
Monroy Muñoz, Francisco
López-Montero, Iván
author_role author
author2 Lillo, M. P.
García Rodríguez, C.
Natale, Paolo
Langevin, D.
Monroy Muñoz, Francisco
López-Montero, Iván
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv Lipids
Monolayers
Compression
Fluids
Phase transitions
Química física (Química)
topic Lipids
Monolayers
Compression
Fluids
Phase transitions
Química física (Química)
description Ceramides have unique biophysical properties. Their high melting temperature and their ability to form lateral domains have converted ceramides into the paradigm of rigid lipids. Here, using shear surface rheology of egg-ceramide Langmuir monolayers, a solid to fluid transition was evidenced as a vanishing shear rigidity at lower temperatures than the lipid melting temperature. Such a mechanical transition, which depends on the lipid lateral pressure, was found in a broad range temperature (40−50 °C). The solid to fluid transition was correlated to a LC to LC+LE phase transition, as confirmed by BAM experiments. Interestingly, together with the softening transition, a supercooling process compatible with a glassy behavior was found upon freezing. A new phase scenario is then depicted that broadens the mechanical behavior of natural ceramides. The phase diversity of ceramides might have important implications in their physiological roles.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01
2015
2015-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/34193
url https://hdl.handle.net/20.500.14352/34193
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
https://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
https://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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