Capillary electrophoresis-electrospraymass spectrometry in peptide analysis and peptidomics

In the present work, an exhaustive review of the main developments and applications of CEMS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different mul...

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Detalles Bibliográficos
Autores: Herrero, Miguel, Ibáñez, Elena, Cifuentes, Alejandro
Tipo de recurso: artículo
Fecha de publicación:2008
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/12396
Acceso en línea:http://hdl.handle.net/10261/12396
Access Level:acceso abierto
Palabra clave:Capillary electrophoresis-mass spectrometry
peptides
Proteomics
Descripción
Sumario:In the present work, an exhaustive review of the main developments and applications of CEMS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different multidimensional strategies for peptide analysis. Key applications are critically discussed and relevant works published from January 2000 to May 2007 are summarized including information concerning the type of sample, CE-MS parameters as well as some figures of merit of the different CE-MS procedures developed for peptide analysis and peptidomics.