Evolution of the odorant-binding protein gene family in Drosophila
Odorant-binding proteins (OBPs) are encoded by a gene family involved in the perception of olfactory signals in insects. This chemosensory gene family has been advocated as a candidate to mediate host preference and host shifts in insects, although it also participates in other physiological process...
| Autores: | , , , , , |
|---|---|
| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/194228 |
| Acesso em linha: | https://hdl.handle.net/2445/194228 |
| Access Level: | acceso abierto |
| Palavra-chave: | Drosòfila Genòmica Adaptació (Fisiologia) Proteïnes Olfacte Drosophila Genomics Adaptation (Physiology) Proteins Smell |
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Evolution of the odorant-binding protein gene family in DrosophilaRondón, Johnma J.Moreyra, Nicolás NahuelPisarenco, Vadim A.Rozas Liras, Julio A.Hurtado, JuanHasson, EstebanDrosòfilaGenòmicaAdaptació (Fisiologia)ProteïnesOlfacteDrosophilaGenomicsAdaptation (Physiology)ProteinsSmellOdorant-binding proteins (OBPs) are encoded by a gene family involved in the perception of olfactory signals in insects. This chemosensory gene family has been advocated as a candidate to mediate host preference and host shifts in insects, although it also participates in other physiological processes. Remarkable differences in the OBP gene repertoire have been described across insect groups, suggesting an accelerated gene turnover rate. The genus Drosophila, is a valuable resource for ecological genomics studies since it comprises groups of ecologically diverse species and there are genome data for many of them. Here, we investigate the molecular evolution of this chemosensory gene family across 19 Drosophila genomes, including the melanogaster and repleta species groups, which are mostly associated with rotting fruit and cacti, respectively. We also compared the OBP repertoire among the closely related species of the repleta group, associated with different subfamilies of Cactaceae that represent disparate chemical challenges for the flies. We found that the gene family size varies widely between species, ranging from 39 to 54 candidate OBPs. Indeed, more than 54% of these genes are organized in clusters and located on chromosomes X, 2, and 5, with a distribution conserved throughout the genus. The family sizes in the repleta group and D. virilis (virilis-repleta radiation) were smaller than in the melanogaster group. We tested alternative evolutionary models for OBP family size and turnover rates based on different ecological scenarios. We found heterogeneous gene turnover rates (GR) in comparisons involving columnar cactus specialists, prickly pear specialists, and fruit dwellers lineages, and signals of rapid molecular evolution compatible with positive selection in specific OBP genes. Taking ours and previous results together, we propose that this chemosensory gene family is involved in host adaptation and hypothesize that the adoption of the cactophilic lifestyle in the repleta group accelerated the evolution of members of the family.Frontiers Media2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/194228Articles publicats en revistes (Genètica, Microbiologia i Estadística)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3389/fevo.2022.957247Frontiers In Ecology And Evolution, 2022, vol. 10, p. 957247https://doi.org/10.3389/fevo.2022.957247cc-by (c) Rondón, Johnma J. et al., 2022https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1942282026-05-27T06:46:51Z |
| dc.title.none.fl_str_mv |
Evolution of the odorant-binding protein gene family in Drosophila |
| title |
Evolution of the odorant-binding protein gene family in Drosophila |
| spellingShingle |
Evolution of the odorant-binding protein gene family in Drosophila Rondón, Johnma J. Drosòfila Genòmica Adaptació (Fisiologia) Proteïnes Olfacte Drosophila Genomics Adaptation (Physiology) Proteins Smell |
| title_short |
Evolution of the odorant-binding protein gene family in Drosophila |
| title_full |
Evolution of the odorant-binding protein gene family in Drosophila |
| title_fullStr |
Evolution of the odorant-binding protein gene family in Drosophila |
| title_full_unstemmed |
Evolution of the odorant-binding protein gene family in Drosophila |
| title_sort |
Evolution of the odorant-binding protein gene family in Drosophila |
| dc.creator.none.fl_str_mv |
Rondón, Johnma J. Moreyra, Nicolás Nahuel Pisarenco, Vadim A. Rozas Liras, Julio A. Hurtado, Juan Hasson, Esteban |
| author |
Rondón, Johnma J. |
| author_facet |
Rondón, Johnma J. Moreyra, Nicolás Nahuel Pisarenco, Vadim A. Rozas Liras, Julio A. Hurtado, Juan Hasson, Esteban |
| author_role |
author |
| author2 |
Moreyra, Nicolás Nahuel Pisarenco, Vadim A. Rozas Liras, Julio A. Hurtado, Juan Hasson, Esteban |
| author2_role |
author author author author author |
| dc.subject.none.fl_str_mv |
Drosòfila Genòmica Adaptació (Fisiologia) Proteïnes Olfacte Drosophila Genomics Adaptation (Physiology) Proteins Smell |
| topic |
Drosòfila Genòmica Adaptació (Fisiologia) Proteïnes Olfacte Drosophila Genomics Adaptation (Physiology) Proteins Smell |
| description |
Odorant-binding proteins (OBPs) are encoded by a gene family involved in the perception of olfactory signals in insects. This chemosensory gene family has been advocated as a candidate to mediate host preference and host shifts in insects, although it also participates in other physiological processes. Remarkable differences in the OBP gene repertoire have been described across insect groups, suggesting an accelerated gene turnover rate. The genus Drosophila, is a valuable resource for ecological genomics studies since it comprises groups of ecologically diverse species and there are genome data for many of them. Here, we investigate the molecular evolution of this chemosensory gene family across 19 Drosophila genomes, including the melanogaster and repleta species groups, which are mostly associated with rotting fruit and cacti, respectively. We also compared the OBP repertoire among the closely related species of the repleta group, associated with different subfamilies of Cactaceae that represent disparate chemical challenges for the flies. We found that the gene family size varies widely between species, ranging from 39 to 54 candidate OBPs. Indeed, more than 54% of these genes are organized in clusters and located on chromosomes X, 2, and 5, with a distribution conserved throughout the genus. The family sizes in the repleta group and D. virilis (virilis-repleta radiation) were smaller than in the melanogaster group. We tested alternative evolutionary models for OBP family size and turnover rates based on different ecological scenarios. We found heterogeneous gene turnover rates (GR) in comparisons involving columnar cactus specialists, prickly pear specialists, and fruit dwellers lineages, and signals of rapid molecular evolution compatible with positive selection in specific OBP genes. Taking ours and previous results together, we propose that this chemosensory gene family is involved in host adaptation and hypothesize that the adoption of the cactophilic lifestyle in the repleta group accelerated the evolution of members of the family. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/2445/194228 |
| url |
https://hdl.handle.net/2445/194228 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Reproducció del document publicat a: https://doi.org/10.3389/fevo.2022.957247 Frontiers In Ecology And Evolution, 2022, vol. 10, p. 957247 https://doi.org/10.3389/fevo.2022.957247 |
| dc.rights.none.fl_str_mv |
cc-by (c) Rondón, Johnma J. et al., 2022 https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
cc-by (c) Rondón, Johnma J. et al., 2022 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Frontiers Media |
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Frontiers Media |
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Articles publicats en revistes (Genètica, Microbiologia i Estadística) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona |
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Universidad de Barcelona |
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Dipòsit Digital de la UB |
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Dipòsit Digital de la UB |
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