Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method

The kinematic behavior of models that are based on the finite element method (FEM) for modeling the human body depends greatly on an accurate estimate of the parameters that define such models. This task is complex, and any small difference between the actual biomaterial model and the simulation mod...

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Autores: Gómez, F.S. [0000-0002-5286-0243], Lorza, R.L. [0000-0001-5902-6078], Bobadilla, M.C. [0000-0002-6057-7077], García, R.E. [0000-0003-2612-942X]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Universidad de La Rioja (UR)
Repositorio:RIUR. Repositorio Institucional de la Universidad de La Rioja
OAI Identifier:oai:portal.dialnet.es:doc/5bbc6948b750603269e81869
Acceso en línea:https://investigacion.unirioja.es/documentos/5bbc6948b750603269e81869
Access Level:acceso abierto
Palabra clave:Biomechanics
Finite Elements Method
Human intervertebral lumbar disc
Multi Response Surface
optimization
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spelling Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface methodGómez, F.S. [0000-0002-5286-0243]Lorza, R.L. [0000-0001-5902-6078]Bobadilla, M.C. [0000-0002-6057-7077]García, R.E. [0000-0003-2612-942X]BiomechanicsFinite Elements MethodHuman intervertebral lumbar discMulti Response SurfaceoptimizationThe kinematic behavior of models that are based on the finite element method (FEM) for modeling the human body depends greatly on an accurate estimate of the parameters that define such models. This task is complex, and any small difference between the actual biomaterial model and the simulation model based on FEM can be amplified enormously in the presence of nonlinearities. The current paper attempts to demonstrate how a combination of the FEM and the MRS methods with desirability functions can be used to obtain the material parameters that are most appropriate for use in defining the behavior of Finite Element (FE) models of the healthy human lumbar intervertebral disc (IVD). The FE model parameters were adjusted on the basis of experimental data from selected standard tests (compression, flexion, extension, shear, lateral bending, and torsion) and were developed as follows: First, three-dimensional parameterized FE models were generated on the basis of the mentioned standard tests. Then, 11 parameters were selected to define the proposed parameterized FE models. For each of the standard tests, regression models were generated using MRS to model the six stiffness and nine bulges of the healthy IVD models that were created by changing the parameters of the FE models. The optimal combination of the 11 parameters was based on three different adjustment criteria. The latter, in turn, were based on the combination of stiffness and bulges that were obtained from the standard test FE simulations. The first adjustment criteria considered stiffness and bulges to be equally important in the adjustment of FE model parameters. The second adjustment criteria considered stiffness as most important, whereas the third considered the bulges to be most important. The proposed adjustment methods were applied to a medium-sized human IVD that corresponded to the L3-L4 lumbar level with standard dimensions of width = 50 mm, depth = 35 mm, and height = 10 mm. Agreement between the kinematic behavior that was obtained with the optimized parameters and that obtained from the literature demonstrated that the proposed method is a powerful tool with which to adjust healthy IVD FE models when there are many parameters, stiffnesses, and bulges to which the models must adjust. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.2017info:eu-repo/semantics/articleSubtype: Articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://investigacion.unirioja.es/documentos/5bbc6948b750603269e81869reponame:RIUR. Repositorio Institucional de la Universidad de La Riojainstname:Universidad de La Rioja (UR)Inglésinfo:eu-repo/semantics/altIdentifier/doi/10.3390/MA10101116info:eu-repo/semantics/altIdentifier/wos/WOS:000414639000011info:eu-repo/semantics/altIdentifier/pissn/1996-1944Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method, 2017, vol. 10, núm. 10info:eu-repo/semantics/openAccessoai:portal.dialnet.es:doc/5bbc6948b750603269e818692026-06-14T12:47:17Z
dc.title.none.fl_str_mv Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
title Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
spellingShingle Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
Gómez, F.S. [0000-0002-5286-0243]
Biomechanics
Finite Elements Method
Human intervertebral lumbar disc
Multi Response Surface
optimization
title_short Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
title_full Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
title_fullStr Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
title_full_unstemmed Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
title_sort Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method
dc.creator.none.fl_str_mv Gómez, F.S. [0000-0002-5286-0243]
Lorza, R.L. [0000-0001-5902-6078]
Bobadilla, M.C. [0000-0002-6057-7077]
García, R.E. [0000-0003-2612-942X]
author Gómez, F.S. [0000-0002-5286-0243]
author_facet Gómez, F.S. [0000-0002-5286-0243]
Lorza, R.L. [0000-0001-5902-6078]
Bobadilla, M.C. [0000-0002-6057-7077]
García, R.E. [0000-0003-2612-942X]
author_role author
author2 Lorza, R.L. [0000-0001-5902-6078]
Bobadilla, M.C. [0000-0002-6057-7077]
García, R.E. [0000-0003-2612-942X]
author2_role author
author
author
dc.subject.none.fl_str_mv Biomechanics
Finite Elements Method
Human intervertebral lumbar disc
Multi Response Surface
optimization
topic Biomechanics
Finite Elements Method
Human intervertebral lumbar disc
Multi Response Surface
optimization
description The kinematic behavior of models that are based on the finite element method (FEM) for modeling the human body depends greatly on an accurate estimate of the parameters that define such models. This task is complex, and any small difference between the actual biomaterial model and the simulation model based on FEM can be amplified enormously in the presence of nonlinearities. The current paper attempts to demonstrate how a combination of the FEM and the MRS methods with desirability functions can be used to obtain the material parameters that are most appropriate for use in defining the behavior of Finite Element (FE) models of the healthy human lumbar intervertebral disc (IVD). The FE model parameters were adjusted on the basis of experimental data from selected standard tests (compression, flexion, extension, shear, lateral bending, and torsion) and were developed as follows: First, three-dimensional parameterized FE models were generated on the basis of the mentioned standard tests. Then, 11 parameters were selected to define the proposed parameterized FE models. For each of the standard tests, regression models were generated using MRS to model the six stiffness and nine bulges of the healthy IVD models that were created by changing the parameters of the FE models. The optimal combination of the 11 parameters was based on three different adjustment criteria. The latter, in turn, were based on the combination of stiffness and bulges that were obtained from the standard test FE simulations. The first adjustment criteria considered stiffness and bulges to be equally important in the adjustment of FE model parameters. The second adjustment criteria considered stiffness as most important, whereas the third considered the bulges to be most important. The proposed adjustment methods were applied to a medium-sized human IVD that corresponded to the L3-L4 lumbar level with standard dimensions of width = 50 mm, depth = 35 mm, and height = 10 mm. Agreement between the kinematic behavior that was obtained with the optimized parameters and that obtained from the literature demonstrated that the proposed method is a powerful tool with which to adjust healthy IVD FE models when there are many parameters, stiffnesses, and bulges to which the models must adjust. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
Subtype: Article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://investigacion.unirioja.es/documentos/5bbc6948b750603269e81869
url https://investigacion.unirioja.es/documentos/5bbc6948b750603269e81869
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/MA10101116
info:eu-repo/semantics/altIdentifier/wos/WOS:000414639000011
info:eu-repo/semantics/altIdentifier/pissn/1996-1944
Improving the process of adjusting the parameters of finite element models of healthy human intervertebral discs by the multi-response surface method, 2017, vol. 10, núm. 10
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:RIUR. Repositorio Institucional de la Universidad de La Rioja
instname:Universidad de La Rioja (UR)
instname_str Universidad de La Rioja (UR)
reponame_str RIUR. Repositorio Institucional de la Universidad de La Rioja
collection RIUR. Repositorio Institucional de la Universidad de La Rioja
repository.name.fl_str_mv
repository.mail.fl_str_mv
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