Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study
On behalf of the HELENA Study Group.
| Autores: | , , , , , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/242278 |
| Acceso en línea: | http://hdl.handle.net/10261/242278 |
| Access Level: | acceso abierto |
| Palabra clave: | Homocysteine Physical activity Cardiovascular fitness Body constitution |
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oai:digital.csic.es:10261/242278 |
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Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA studyBenser, J.Valtueña, JaraRuiz, Jonatan R.Mielgo-Ayuso, JuanBreidenassel, ChristinaVicente-Rodríguez, G.Ferrari, MarikaWidhalm, KurtManios, YannisSjöström, MichaelMolnár, DénesGómez-Martínez, SoniaKafatos, AnthonyPalacios, GonzaloMoreno, Luis A.Castillo, Manuel J.Stehle, PeterGonzález-Gross, MarcelaHomocysteinePhysical activityCardiovascular fitnessBody constitutionOn behalf of the HELENA Study Group.We examined the association of physical activity (PA), cardiovascular fitness (CVF) and fatness with total homocysteine (tHcy) concentrations in European adolescents. The present study comprised 713 European adolescents aged 14.8±1.2 y (females 55.3%) from the multicenter HELENA cross-sectional study. PA was assessed through accelerometry, CVF by the 20-m shuttle run test, and body fat by skinfold thicknesses with the Slaughter equation. Plasma folate, cobalamin, and tHcy concentrations were measured. To examine the association of tHcy with PA, CVF, and fatness after controlling for a set of confounders including age, maturity, folate, cobalamin, creatinine, smoking, supplement use, and methylenetetrahydrofolate reductase 677 genotype (CC 47%, CT 43%, TT 10%), bivariate correlations followed by multiple regression models were performed. In the bivariate correlation analysis, tHcy concentrations were slightly negatively correlated (p<0.05) with CVF in females (measured both by stages: r=−0.118 and by VO2max: r=−0.102) and positively with body mass index (r=0.100). However, daily time spent with moderate and vigorous PA showed a weak positive association with tHcy in females (p<0.05). tHcy concentrations showed a tendency to decrease with increasing CVF and increase with increasing BMI in female European adolescents. However, tHcy concentrations were positively associated with moderate and vigorous PA in female European adolescents.The HELENA study has taken place with the financial support of the European Community Sixth RTD Framework Programme (Contract FOOD-CT-2005-007034). Additional support came in the form of by grants from the Spanish Ministry of Education (EX-2007-1124, EX-2008-0641, AP2006-02464; AGL2007-29784-E/ ALI; AP-2005-3827), the Spanish Ministry of Economy and Competitiveness (RYC-2010-05957), Universidad Politécnica de Madrid (CH/018/2008), Swedish Council for Working Life and Social Research, the ALPHA study, a European Union-funded study, in the framework of the Public Health Programme (Ref: 2006120), and the Spanish Ministry of Health: Maternal, Child Health and Development Network (number RD08/0072).Peer reviewedCenter for Academic Publications JapanEuropean CommissionMinisterio de Educación (España)Ministerio de Economía y Competitividad (España)Universidad Politécnica de MadridSwedish Council for Working Life and Social ResearchConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202120212015info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/242278reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.3177/jnsv.61.45Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2422782026-05-22T06:33:51Z |
| dc.title.none.fl_str_mv |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| title |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| spellingShingle |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study Benser, J. Homocysteine Physical activity Cardiovascular fitness Body constitution |
| title_short |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| title_full |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| title_fullStr |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| title_full_unstemmed |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| title_sort |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study |
| dc.creator.none.fl_str_mv |
Benser, J. Valtueña, Jara Ruiz, Jonatan R. Mielgo-Ayuso, Juan Breidenassel, Christina Vicente-Rodríguez, G. Ferrari, Marika Widhalm, Kurt Manios, Yannis Sjöström, Michael Molnár, Dénes Gómez-Martínez, Sonia Kafatos, Anthony Palacios, Gonzalo Moreno, Luis A. Castillo, Manuel J. Stehle, Peter González-Gross, Marcela |
| author |
Benser, J. |
| author_facet |
Benser, J. Valtueña, Jara Ruiz, Jonatan R. Mielgo-Ayuso, Juan Breidenassel, Christina Vicente-Rodríguez, G. Ferrari, Marika Widhalm, Kurt Manios, Yannis Sjöström, Michael Molnár, Dénes Gómez-Martínez, Sonia Kafatos, Anthony Palacios, Gonzalo Moreno, Luis A. Castillo, Manuel J. Stehle, Peter González-Gross, Marcela |
| author_role |
author |
| author2 |
Valtueña, Jara Ruiz, Jonatan R. Mielgo-Ayuso, Juan Breidenassel, Christina Vicente-Rodríguez, G. Ferrari, Marika Widhalm, Kurt Manios, Yannis Sjöström, Michael Molnár, Dénes Gómez-Martínez, Sonia Kafatos, Anthony Palacios, Gonzalo Moreno, Luis A. Castillo, Manuel J. Stehle, Peter González-Gross, Marcela |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
European Commission Ministerio de Educación (España) Ministerio de Economía y Competitividad (España) Universidad Politécnica de Madrid Swedish Council for Working Life and Social Research Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Homocysteine Physical activity Cardiovascular fitness Body constitution |
| topic |
Homocysteine Physical activity Cardiovascular fitness Body constitution |
| description |
On behalf of the HELENA Study Group. |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015 2021 2021 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion |
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article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10261/242278 |
| url |
http://hdl.handle.net/10261/242278 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
https://doi.org/10.3177/jnsv.61.45 Sí |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Center for Academic Publications Japan |
| publisher.none.fl_str_mv |
Center for Academic Publications Japan |
| dc.source.none.fl_str_mv |
reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC) |
| instname_str |
Consejo Superior de Investigaciones Científicas (CSIC) |
| reponame_str |
DIGITAL.CSIC. Repositorio Institucional del CSIC |
| collection |
DIGITAL.CSIC. Repositorio Institucional del CSIC |
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1869416609362214912 |
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15,811543 |