Palliative care for children with central nervous system tumors: results of a Spanish multicenter study

BackgroundBrain tumors represent the most common cause of cancer-related death in children. Few studies concerning the palliative phase in children with brain tumors are available.Objectives(i) To describe the palliative phase in children with brain tumors; (ii) to determine whether the use of palli...

Descripción completa

Detalles Bibliográficos
Autores: Pérez-Torres Lobato M, Navarro-Marchena L, de Noriega I, Morey Olivé M, Solano-Páez P, Rubio Pérez E, Garrido Colino C, García Abos M, Tallón García M, Huidobro Labarga B, Portugal Rodríguez R, López Ibor B, Lassaletta Á, Morgenstern Isaak A, Cruz Martínez O, Valero Arrese L, Llort Sales A, Gros Subias L, Márquez Vega C, Moreno L, Quiroga-Cantero E
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p24874
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24874
Access Level:acceso abierto
Palabra clave:End-of-life
Palliative
Brain tumor
CNS tumor
Neuro-oncology
Childhood cancer
id ES_aeb95fa29a4eecd44890bd98d65e7fd5
oai_identifier_str oai:fsjd.fundanetsuite.com:p24874
network_acronym_str ES
network_name_str España
repository_id_str
spelling Palliative care for children with central nervous system tumors: results of a Spanish multicenter studyPérez-Torres Lobato MNavarro-Marchena Lde Noriega IMorey Olivé MSolano-Páez PRubio Pérez EGarrido Colino CGarcía Abos MTallón García MHuidobro Labarga BPortugal Rodríguez RLópez Ibor BLassaletta ÁMorgenstern Isaak ACruz Martínez OValero Arrese LLlort Sales AGros Subias LMárquez Vega CMoreno LQuiroga-Cantero EEnd-of-lifePalliativeBrain tumorCNS tumorNeuro-oncologyChildhood cancerBackgroundBrain tumors represent the most common cause of cancer-related death in children. Few studies concerning the palliative phase in children with brain tumors are available.Objectives(i) To describe the palliative phase in children with brain tumors; (ii) to determine whether the use of palliative sedation (PS) depends on the place of death, the age of the patient, or if they received specific palliative care (PC).MethodsRetrospective multicenter study between 2010 and 2021, including children from one month to 18 years, who had died of a brain tumor.Results228 patients (59.2% male) from 10 Spanish institutions were included. Median age at diagnosis was 5 years (IQR 2-9) and median age at death was 7 years (IQR 4-11). The most frequent tumors were medulloblastoma (25.4%) and diffuse intrinsic pontine glioma (DIPG) (24.1%). Median number of antineoplastic regimens were 2 (range 0-5 regimens). During palliative phase, 52.2% of the patients were attended by PC teams, while 47.8% were cared exclusively by pediatric oncology teams. Most common concerns included motor deficit (93.4%) and asthenia (87.5%) and communication disorders (89.8%). Most frequently prescribed supportive drugs were antiemetics (83.6%), opioids (81.6%), and dexamethasone (78.5%). PS was administered to 48.7% patients. Most of them died in the hospital (85.6%), while patients who died at home required PS less frequently (14.4%) (p = .01).ConclusionChildren dying from CNS tumors have specific needs during palliative phase. The optimal indication of PS depended on the center experience although, in our series, it was also influenced by the place of death.SPRINGER INT PUBL AG2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24874Clinical & Translational OncologyISSN: 1699048XISSNe: 16993055reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p248742026-05-27T12:37:41Z
dc.title.none.fl_str_mv Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
title Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
spellingShingle Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
Pérez-Torres Lobato M
End-of-life
Palliative
Brain tumor
CNS tumor
Neuro-oncology
Childhood cancer
title_short Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
title_full Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
title_fullStr Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
title_full_unstemmed Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
title_sort Palliative care for children with central nervous system tumors: results of a Spanish multicenter study
dc.creator.none.fl_str_mv Pérez-Torres Lobato M
Navarro-Marchena L
de Noriega I
Morey Olivé M
Solano-Páez P
Rubio Pérez E
Garrido Colino C
García Abos M
Tallón García M
Huidobro Labarga B
Portugal Rodríguez R
López Ibor B
Lassaletta Á
Morgenstern Isaak A
Cruz Martínez O
Valero Arrese L
Llort Sales A
Gros Subias L
Márquez Vega C
Moreno L
Quiroga-Cantero E
author Pérez-Torres Lobato M
author_facet Pérez-Torres Lobato M
Navarro-Marchena L
de Noriega I
Morey Olivé M
Solano-Páez P
Rubio Pérez E
Garrido Colino C
García Abos M
Tallón García M
Huidobro Labarga B
Portugal Rodríguez R
López Ibor B
Lassaletta Á
Morgenstern Isaak A
Cruz Martínez O
Valero Arrese L
Llort Sales A
Gros Subias L
Márquez Vega C
Moreno L
Quiroga-Cantero E
author_role author
author2 Navarro-Marchena L
de Noriega I
Morey Olivé M
Solano-Páez P
Rubio Pérez E
Garrido Colino C
García Abos M
Tallón García M
Huidobro Labarga B
Portugal Rodríguez R
López Ibor B
Lassaletta Á
Morgenstern Isaak A
Cruz Martínez O
Valero Arrese L
Llort Sales A
Gros Subias L
Márquez Vega C
Moreno L
Quiroga-Cantero E
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv End-of-life
Palliative
Brain tumor
CNS tumor
Neuro-oncology
Childhood cancer
topic End-of-life
Palliative
Brain tumor
CNS tumor
Neuro-oncology
Childhood cancer
description BackgroundBrain tumors represent the most common cause of cancer-related death in children. Few studies concerning the palliative phase in children with brain tumors are available.Objectives(i) To describe the palliative phase in children with brain tumors; (ii) to determine whether the use of palliative sedation (PS) depends on the place of death, the age of the patient, or if they received specific palliative care (PC).MethodsRetrospective multicenter study between 2010 and 2021, including children from one month to 18 years, who had died of a brain tumor.Results228 patients (59.2% male) from 10 Spanish institutions were included. Median age at diagnosis was 5 years (IQR 2-9) and median age at death was 7 years (IQR 4-11). The most frequent tumors were medulloblastoma (25.4%) and diffuse intrinsic pontine glioma (DIPG) (24.1%). Median number of antineoplastic regimens were 2 (range 0-5 regimens). During palliative phase, 52.2% of the patients were attended by PC teams, while 47.8% were cared exclusively by pediatric oncology teams. Most common concerns included motor deficit (93.4%) and asthenia (87.5%) and communication disorders (89.8%). Most frequently prescribed supportive drugs were antiemetics (83.6%), opioids (81.6%), and dexamethasone (78.5%). PS was administered to 48.7% patients. Most of them died in the hospital (85.6%), while patients who died at home required PS less frequently (14.4%) (p = .01).ConclusionChildren dying from CNS tumors have specific needs during palliative phase. The optimal indication of PS depended on the center experience although, in our series, it was also influenced by the place of death.
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24874
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=24874
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SPRINGER INT PUBL AG
publisher.none.fl_str_mv SPRINGER INT PUBL AG
dc.source.none.fl_str_mv Clinical & Translational Oncology
ISSN: 1699048X
ISSNe: 16993055
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416605406986240
score 15,811543

Similares en LA Referencia