Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism

© 2018 Wiley Periodicals, Inc. The western European house mouse (Mus musculus domesticus) shows high karyotypic diversity owing to Robertsonian translocations. Morphometric studies conducted with adult mice suggest that karyotype evolution due to these chromosomal reorganizations entails variation i...

Descripción completa

Detalles Bibliográficos
Autores: Martínez Vargas, Jessica|||0000-0003-4689-5228, Muñoz Muñoz, Francesc|||0000-0003-2084-0368, López Fuster, María José|||0000-0002-9955-8973, Cubo, Jorge, Ventura Queija, Jacinto|||0000-0001-7527-1532
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:324357
Acceso en línea:https://ddd.uab.cat/record/324357
Access Level:acceso abierto
Palabra clave:Mus musculus domesticus
Robertsonian translocations
Bone histology
Bone remodeling
Geometric morphometrics
id ES_ae71da1fd302c72899b1e9f836b7ca4e
oai_identifier_str oai:ddd.uab.cat:324357
network_acronym_str ES
network_name_str España
repository_id_str
spelling Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian PolymorphismMartínez Vargas, Jessica|||0000-0003-4689-5228Muñoz Muñoz, Francesc|||0000-0003-2084-0368López Fuster, María José|||0000-0002-9955-8973Cubo, JorgeVentura Queija, Jacinto|||0000-0001-7527-1532Mus musculus domesticusRobertsonian translocationsBone histologyBone remodelingGeometric morphometrics© 2018 Wiley Periodicals, Inc. The western European house mouse (Mus musculus domesticus) shows high karyotypic diversity owing to Robertsonian translocations. Morphometric studies conducted with adult mice suggest that karyotype evolution due to these chromosomal reorganizations entails variation in the form and the patterns of morphological covariation of the mandible. However, information is much scarcer regarding the effect of these rearrangements on the growth pattern of the mouse mandible over early postnatal ontogeny. Here we compare mandible growth from the second to the eighth week of postnatal life between two ontogenetic series of mice from wild populations, with the standard karyotype and with Robertsonian translocations respectively, reared under the same conditions. A multi-method approach is used, including bone histology analyses of mandible surfaces and cross-sections, as well as geometric morphometric analyses of mandible form. The mandibles of both standard and Robertsonian mice display growth acceleration around weaning, anteroposterior direction of bone maturation, a predominance of bone deposition fields over ontogeny, and relatively greater expansion of the posterior mandible region correlated with the ontogenetic increase in mandible size. Nevertheless, differences exist between the two mouse groups regarding the timing of histological maturation of the mandible, the localization of certain bone remodeling fields, the temporospatial patterns of morphological variation, and the organization into two main modules. The dissimilarities in the process of mandible growth between the two groups of mice become more evident around sexual maturity, and could arise from alterations that Robertsonian translocations may exert on genes involved in the bone remodeling mechanism. Anat Rec, 2018. © 2018 Wiley Periodicals, Inc. 22018-01-0120182018-01-01Articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/324357reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.https://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3243572026-06-06T12:50:31Z
dc.title.none.fl_str_mv Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
title Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
spellingShingle Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
Martínez Vargas, Jessica|||0000-0003-4689-5228
Mus musculus domesticus
Robertsonian translocations
Bone histology
Bone remodeling
Geometric morphometrics
title_short Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
title_full Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
title_fullStr Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
title_full_unstemmed Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
title_sort Multimethod Approach to the Early Postnatal Growth of the Mandible in Mice from a Zone of Robertsonian Polymorphism
dc.creator.none.fl_str_mv Martínez Vargas, Jessica|||0000-0003-4689-5228
Muñoz Muñoz, Francesc|||0000-0003-2084-0368
López Fuster, María José|||0000-0002-9955-8973
Cubo, Jorge
Ventura Queija, Jacinto|||0000-0001-7527-1532
author Martínez Vargas, Jessica|||0000-0003-4689-5228
author_facet Martínez Vargas, Jessica|||0000-0003-4689-5228
Muñoz Muñoz, Francesc|||0000-0003-2084-0368
López Fuster, María José|||0000-0002-9955-8973
Cubo, Jorge
Ventura Queija, Jacinto|||0000-0001-7527-1532
author_role author
author2 Muñoz Muñoz, Francesc|||0000-0003-2084-0368
López Fuster, María José|||0000-0002-9955-8973
Cubo, Jorge
Ventura Queija, Jacinto|||0000-0001-7527-1532
author2_role author
author
author
author
dc.subject.none.fl_str_mv Mus musculus domesticus
Robertsonian translocations
Bone histology
Bone remodeling
Geometric morphometrics
topic Mus musculus domesticus
Robertsonian translocations
Bone histology
Bone remodeling
Geometric morphometrics
description © 2018 Wiley Periodicals, Inc. The western European house mouse (Mus musculus domesticus) shows high karyotypic diversity owing to Robertsonian translocations. Morphometric studies conducted with adult mice suggest that karyotype evolution due to these chromosomal reorganizations entails variation in the form and the patterns of morphological covariation of the mandible. However, information is much scarcer regarding the effect of these rearrangements on the growth pattern of the mouse mandible over early postnatal ontogeny. Here we compare mandible growth from the second to the eighth week of postnatal life between two ontogenetic series of mice from wild populations, with the standard karyotype and with Robertsonian translocations respectively, reared under the same conditions. A multi-method approach is used, including bone histology analyses of mandible surfaces and cross-sections, as well as geometric morphometric analyses of mandible form. The mandibles of both standard and Robertsonian mice display growth acceleration around weaning, anteroposterior direction of bone maturation, a predominance of bone deposition fields over ontogeny, and relatively greater expansion of the posterior mandible region correlated with the ontogenetic increase in mandible size. Nevertheless, differences exist between the two mouse groups regarding the timing of histological maturation of the mandible, the localization of certain bone remodeling fields, the temporospatial patterns of morphological variation, and the organization into two main modules. The dissimilarities in the process of mandible growth between the two groups of mice become more evident around sexual maturity, and could arise from alterations that Robertsonian translocations may exert on genes involved in the bone remodeling mechanism. Anat Rec, 2018. © 2018 Wiley Periodicals, Inc.
publishDate 2018
dc.date.none.fl_str_mv 2
2018-01-01
2018
2018-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/324357
url https://ddd.uab.cat/record/324357
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416562310512640
score 15,811543

Similares en LA Referencia