Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD

Producción Científica

Detalles Bibliográficos
Autores: Coca Rojo, Armando, Burballa Tarrega, Carla Cristina, Centellas-Pérez, Francisco Javier, Pérez Saéz, María José, Bustamante Munguira, Elena, Ortega, Agustín, Dueñas, Carlos, Arenas, María Dolores, Pérez-Martínez, Juan, Ruiz, Guadalupe, Crespo Barrio, Marta, Llamas, Francisco, Bustamante Munguira, Juan, Pascual Santos, Julio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/82126
Acceso en línea:https://doi.org/10.3389/fmed.2020.615312
https://uvadoc.uva.es/handle/10324/82126
Access Level:acceso abierto
Palabra clave:COVID-19
Kidneys - Diseases
Riñones - Enfermedades
Nephrology
Pneumònia
Neumonía
Acute renal failure
Insuficiencia renal aguda
3205.06 Nefrología
32 Ciencias Médicas
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network_name_str España
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spelling Outcomes of COVID-19 among hospitalized patients with non-dialysis CKDCoca Rojo, ArmandoBurballa Tarrega, Carla CristinaCentellas-Pérez, Francisco JavierPérez Saéz, María JoséBustamante Munguira, ElenaOrtega, AgustínDueñas, CarlosArenas, María DoloresPérez-Martínez, JuanRuiz, GuadalupeCrespo Barrio, MartaLlamas, FranciscoBustamante Munguira, JuanPascual Santos, JulioCOVID-19Kidneys - DiseasesRiñones - EnfermedadesNephrologyPneumòniaNeumoníaAcute renal failureInsuficiencia renal aguda3205.06 Nefrología32 Ciencias MédicasProducción CientíficaBackground: Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Corona Virus 2 has generated significant impact on global health worldwide. COVID-19 can cause pneumonia and organ injury. Chronic kidney disease (CKD) has been associated with increased mortality in previous epidemics, but there is a paucity of data regarding actual risks for non-dialysis CKD patients with COVID-19. Methods: Multicenter, observational cohort study including 136 non-dialysis CKD patients and 136 age- and sex-matched controls that required hospitalization due to COVID-19. Patients with end-stage renal disease, a kidney transplant or without registered baseline glomerular filtration rate prior to COVID-19 infection were excluded. CKD and acute kidney injury (AKI) were defined according to KDIGO criteria. Results: CKD patients had higher white blood cell count and D-dimer and lower lymphocyte percentage. No differences were found regarding symptoms on admission. CKD was associated with higher rate of AKI (61 vs. 24.3%) and mortality (40.4 vs. 24.3%). Patients with AKI had the highest hazard for death (AKI/non-CKD HR:7.04, 95% CI:2.87-17.29; AKI/CKD HR:5.25, 95% CI: 2.29-12.02), followed by CKD subjects without AKI (HR:3.39, 95% CI:1.36-8.46). CKD status did not condition ICU admission or length of in-hospital stay. Conclusions: CKD patients that require hospitalization due to COVID-19 are exposed to higher risk of death and AKI.Consejería de Sanidad, Junta de Castilla y León (GRS1732/A/18 and GRS 1969/A/19).Frontiers in medicine2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3389/fmed.2020.615312https://uvadoc.uva.es/handle/10324/82126reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.615312/fullinfo:eu-repo/semantics/openAccessoai:uvadoc.uva.es:10324/821262026-06-13T12:44:47Z
dc.title.none.fl_str_mv Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
title Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
spellingShingle Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
Coca Rojo, Armando
COVID-19
Kidneys - Diseases
Riñones - Enfermedades
Nephrology
Pneumònia
Neumonía
Acute renal failure
Insuficiencia renal aguda
3205.06 Nefrología
32 Ciencias Médicas
title_short Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
title_full Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
title_fullStr Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
title_full_unstemmed Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
title_sort Outcomes of COVID-19 among hospitalized patients with non-dialysis CKD
dc.creator.none.fl_str_mv Coca Rojo, Armando
Burballa Tarrega, Carla Cristina
Centellas-Pérez, Francisco Javier
Pérez Saéz, María José
Bustamante Munguira, Elena
Ortega, Agustín
Dueñas, Carlos
Arenas, María Dolores
Pérez-Martínez, Juan
Ruiz, Guadalupe
Crespo Barrio, Marta
Llamas, Francisco
Bustamante Munguira, Juan
Pascual Santos, Julio
author Coca Rojo, Armando
author_facet Coca Rojo, Armando
Burballa Tarrega, Carla Cristina
Centellas-Pérez, Francisco Javier
Pérez Saéz, María José
Bustamante Munguira, Elena
Ortega, Agustín
Dueñas, Carlos
Arenas, María Dolores
Pérez-Martínez, Juan
Ruiz, Guadalupe
Crespo Barrio, Marta
Llamas, Francisco
Bustamante Munguira, Juan
Pascual Santos, Julio
author_role author
author2 Burballa Tarrega, Carla Cristina
Centellas-Pérez, Francisco Javier
Pérez Saéz, María José
Bustamante Munguira, Elena
Ortega, Agustín
Dueñas, Carlos
Arenas, María Dolores
Pérez-Martínez, Juan
Ruiz, Guadalupe
Crespo Barrio, Marta
Llamas, Francisco
Bustamante Munguira, Juan
Pascual Santos, Julio
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv COVID-19
Kidneys - Diseases
Riñones - Enfermedades
Nephrology
Pneumònia
Neumonía
Acute renal failure
Insuficiencia renal aguda
3205.06 Nefrología
32 Ciencias Médicas
topic COVID-19
Kidneys - Diseases
Riñones - Enfermedades
Nephrology
Pneumònia
Neumonía
Acute renal failure
Insuficiencia renal aguda
3205.06 Nefrología
32 Ciencias Médicas
description Producción Científica
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3389/fmed.2020.615312
https://uvadoc.uva.es/handle/10324/82126
url https://doi.org/10.3389/fmed.2020.615312
https://uvadoc.uva.es/handle/10324/82126
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.615312/full
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers in medicine
publisher.none.fl_str_mv Frontiers in medicine
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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