Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity

To evaluate differences in maternal lines to the immune response of reproductive rabbit does, a total of 64 animals of two different lines: (1) founded for hyper-longevity and litter size criteria (LP) and (2) selected for litter size at weaning (V) were used. Females were subjected to three differe...

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Autores: Ferrian, Selena, Blas Ferrer, Enrique, Larsen, T., Sánchez Serrano, Juan Pablo, Friggens, Nicholas Charles, Corpa, J. M., Baselga Izquierdo, Manuel, Pascual Amorós, Juan José|||0000-0002-7224-9978
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/61549
Acceso en línea:https://riunet.upv.es/handle/10251/61549
Access Level:acceso abierto
Palabra clave:Rabbit doe
Immunological challenge
Genetic selection
Litter size
Longevity
PRODUCCION ANIMAL
NUTRICION Y BROMATOLOGIA
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spelling Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevityFerrian, SelenaBlas Ferrer, EnriqueLarsen, T.Sánchez Serrano, Juan PabloFriggens, Nicholas CharlesCorpa, J. M.Baselga Izquierdo, ManuelPascual Amorós, Juan José|||0000-0002-7224-9978Rabbit doeImmunological challengeGenetic selectionLitter sizeLongevityPRODUCCION ANIMALNUTRICION Y BROMATOLOGIATo evaluate differences in maternal lines to the immune response of reproductive rabbit does, a total of 64 animals of two different lines: (1) founded for hyper-longevity and litter size criteria (LP) and (2) selected for litter size at weaning (V) were used. Females were subjected to three different reproductive efforts: post-partum (PP) mating at first lactation and 9 kits during the second; post-weaning (PW) mating at first lactation and 9 kits during the second; and PW mating at first lactation and 5 kits during the second. At second weaning (30 days PP), an acute response was induced by intravenous infusion of lipopolysaccharide (LPS). LP females seemed to be lower affected during the hyper-acute phase than V females, showing lower plasma glucose content at 1.5 h post infusion (pi) and rectal temperature at 6 h pi; and showed higher ulterior immune response, with higher levels of C-reactive protein at 48 h pi and haptoglobin in plasma from 24 h pi. Survival test conferred a higher risk of culling for V than for LP females during the first hours after challenge. These results may suggest that, regarding immune response to LPS challenge, foundation by hyper-longevity productive criteria lead to obtain a more robust population of rabbit does, characterized by improved response ability. (C) 2013 Elsevier Ltd. All rights reserved.This study has been supported by the Interministerial Commission for Science and Technology (CICYT) from the Spanish Government. Grants Number: AGL2011-30170-C02-01; AGL2011-30170-C02-02), is gratefully acknowledged.ElsevierDepartamento de Ciencia AnimalInstituto Universitario de Ciencia y Tecnología AnimalEscuela Técnica Superior de Ingeniería Agronómica y del Medio NaturalMinisterio de Ciencia e InnovaciónRepositorio Institucional de la Universitat Politècnica de València Riunet20132013-06-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://riunet.upv.es/handle/10251/61549reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengMinisterio de Ciencia e Innovación http://dx.doi.org/10.13039/501100004837 AGL2011-30170-C02-02 ESTUDIO DEL SISTEMA INMUNE DE DIFERENTES LINEAS GENETICAS CUNICOLAS Y SU RESPUESTA FRENTE A DESAFIOS PRODUCTIVOS E INFECCIOSOSopen accesshttp://purl.org/coar/access_right/c_abf2Reserva de todos los derechoshttp://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/615492026-06-13T07:49:27Z
dc.title.none.fl_str_mv Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
title Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
spellingShingle Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
Ferrian, Selena
Rabbit doe
Immunological challenge
Genetic selection
Litter size
Longevity
PRODUCCION ANIMAL
NUTRICION Y BROMATOLOGIA
title_short Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
title_full Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
title_fullStr Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
title_full_unstemmed Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
title_sort Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity
dc.creator.none.fl_str_mv Ferrian, Selena
Blas Ferrer, Enrique
Larsen, T.
Sánchez Serrano, Juan Pablo
Friggens, Nicholas Charles
Corpa, J. M.
Baselga Izquierdo, Manuel
Pascual Amorós, Juan José|||0000-0002-7224-9978
author Ferrian, Selena
author_facet Ferrian, Selena
Blas Ferrer, Enrique
Larsen, T.
Sánchez Serrano, Juan Pablo
Friggens, Nicholas Charles
Corpa, J. M.
Baselga Izquierdo, Manuel
Pascual Amorós, Juan José|||0000-0002-7224-9978
author_role author
author2 Blas Ferrer, Enrique
Larsen, T.
Sánchez Serrano, Juan Pablo
Friggens, Nicholas Charles
Corpa, J. M.
Baselga Izquierdo, Manuel
Pascual Amorós, Juan José|||0000-0002-7224-9978
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Ciencia Animal
Instituto Universitario de Ciencia y Tecnología Animal
Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural
Ministerio de Ciencia e Innovación
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Rabbit doe
Immunological challenge
Genetic selection
Litter size
Longevity
PRODUCCION ANIMAL
NUTRICION Y BROMATOLOGIA
topic Rabbit doe
Immunological challenge
Genetic selection
Litter size
Longevity
PRODUCCION ANIMAL
NUTRICION Y BROMATOLOGIA
description To evaluate differences in maternal lines to the immune response of reproductive rabbit does, a total of 64 animals of two different lines: (1) founded for hyper-longevity and litter size criteria (LP) and (2) selected for litter size at weaning (V) were used. Females were subjected to three different reproductive efforts: post-partum (PP) mating at first lactation and 9 kits during the second; post-weaning (PW) mating at first lactation and 9 kits during the second; and PW mating at first lactation and 5 kits during the second. At second weaning (30 days PP), an acute response was induced by intravenous infusion of lipopolysaccharide (LPS). LP females seemed to be lower affected during the hyper-acute phase than V females, showing lower plasma glucose content at 1.5 h post infusion (pi) and rectal temperature at 6 h pi; and showed higher ulterior immune response, with higher levels of C-reactive protein at 48 h pi and haptoglobin in plasma from 24 h pi. Survival test conferred a higher risk of culling for V than for LP females during the first hours after challenge. These results may suggest that, regarding immune response to LPS challenge, foundation by hyper-longevity productive criteria lead to obtain a more robust population of rabbit does, characterized by improved response ability. (C) 2013 Elsevier Ltd. All rights reserved.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-06-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/61549
url https://riunet.upv.es/handle/10251/61549
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Ciencia e Innovación http://dx.doi.org/10.13039/501100004837 AGL2011-30170-C02-02 ESTUDIO DEL SISTEMA INMUNE DE DIFERENTES LINEAS GENETICAS CUNICOLAS Y SU RESPUESTA FRENTE A DESAFIOS PRODUCTIVOS E INFECCIOSOS
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300719

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