Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture

Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C-3(LA)(2)) indi...

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Detalles Bibliográficos
Autores: Coronel León, Jonathan, Pinazo Gassol, Aurora, Pérez Muñoz, Lourdes, Espuny Tomás, Ma. José (María José), Marqués Villavecchia, Ana M., Manresa Presas, Ma. Ángeles (María Ángeles)
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/169453
Acceso en línea:https://hdl.handle.net/2445/169453
Access Level:acceso abierto
Palabra clave:Agents tensioactius
Aminoàcids
Microbiologia
Surface active agents
Amino acids
Microbiology
Descripción
Sumario:Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C-3(LA)(2)) indicate a strong interaction suggesting the formation of a new 'pseudo-surfactant'. The antimicrobial properties of the mixture lichenysin and C-3(LA)(2) M80:20, indicate a synergistic effect of the components. The mechanism of action on the bacterial envelope was assessed by flow cytometry and Transmission Electron Microscopy. (C) 2016 Elsevier B.V. All rights reserved. Keywords: Antimicrobial properties; Arginine; Escherichia coli; Flow cytometry; Gemini surfactants; Lichenysin; Listeria nonocytogenes; Potassium leakage; Transmission electron microscopy.