Antiviral and antioxidant properties of active alginate edible films containing phenolic extracts

In this work, novel active edible films having antiviral activity were developed through the solvent casting method. Emulsified edible films were prepared by adding lipids into alginate films in order to improve their water vapour permeability. In addition, two natural extracts rich in phenolic comp...

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Detalhes bibliográficos
Autores: Fabra, María José, Falcó, Irene, Randazzo, Walter, Sánchez Moragas, Gloria, López-Rubio, Amparo
Tipo de documento: artigo
Estado:Versión aceptada para publicación
Data de publicação:2018
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/162633
Acesso em linha:http://hdl.handle.net/10261/162633
Access Level:Acceso aberto
Palavra-chave:Enteric viruses
Active packaging
Edible films
Grape seed extract (GSE)
Green tee extract (GTE)
Descrição
Resumo:In this work, novel active edible films having antiviral activity were developed through the solvent casting method. Emulsified edible films were prepared by adding lipids into alginate films in order to improve their water vapour permeability. In addition, two natural extracts rich in phenolic compounds, specifically a green tea extract (GTE) and a grape seed extract (GSE) were used as active agents. Interestingly, incorporating GTE or GSE within the biopolymer matrix, the films exhibited significant antiviral activity against murine norovirus (MNV) and hepatitis A virus (HAV) since ∼2 log reduction were recorded for the 0.75 g extract/g alginate in the film, being GTE more efficient than GSE. Furthermore, the incorporation of phenolic compounds imparted antioxidant capacity to the active films, showing 14.79 ± 0.25 and 3.50 ± 0.25 mM Trolox⋅ g extract in the film−1 for 0.75 GTE and 0.75 GSE films, respectively. It was also found that water barrier efficiency improved upon addition of the highest amount of GTE or GSE (1:0.75 alginate:extract ratio) which was ascribed to molecular interactions between the films' components, as demonstrated by infrared spectroscopy assays.