Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain
Purpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are challenging to diagnose and manage, with substan...
| Autores: | , , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de publicación: | 2023 |
| País: | España |
| Recursos: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:280824 |
| Acesso em linha: | https://ddd.uab.cat/record/280824 https://dx.doi.org/urn:doi:10.1007/s00408-023-00620-y |
| Access Level: | acceso abierto |
| Palavra-chave: | Health resource utilization Noninterventional study Refractory chronic cough Spain Unexplained chronic cough |
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Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in SpainA Retrospective Multicenter StudyDomingo, Christian|||0000-0001-8358-773XDávila, Ignacio|||0000-0001-8485-5513Puente, Luis|||0000-0001-8501-0117Quirce Gancedo, Santiago|||0000-0001-8086-0921Arismendi, Ebymar|||0000-0002-7749-2838Díaz Palacios, MiguelPereira-Vega, Antonio|||0000-0002-6281-4793De Diego, AlfredoRodriguez Hermosa, Juan Luis|||0000-0003-0552-2484Cea-Calvo, LuisSánchez-Jareño, MartaLópez Cotarelo, PilarHealth resource utilizationNoninterventional studyRefractory chronic coughSpainUnexplained chronic coughPurpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are challenging to diagnose and manage, with substantial economic implications for healthcare systems. Methods: This retrospective multicenter non-interventional study aimed to characterize the profile and health resource consumption of patients with RCC or UCC who attended outpatient clinics at Spanish hospitals. Data were collected from medical records of patients with RCC or UCC for up to 3 years before study inclusion. Results: The patient cohort (n = 196) was representative of the chronic cough population (77.6% female, mean age 58.5 years). Two-thirds of patients (n = 126) had RCC. The most frequently visited doctors were pulmonologists (93.4% of patients) and primary care physicians (78.6%), with a mean of 5 visits per patient over three years' observation. The most common diagnostic tests were chest x-ray (83.7%) and spirometry with bronchodilation (77.0%). The most commonly prescribed treatments were proton pump inhibitors (79.6%) and respiratory medications (87.8%). Antibiotics were prescribed empirically to 56 (28.6%) patients. Differences between RCC or UCC groups related mainly to approaches used to manage cough-associated conditions (gastroesophageal reflux disease, asthma) in patients with RCC. Conclusion: RCC and UCC are responsible for high health resource utilization in Spanish hospitals. Specific treatments targeting the pathological processes driving chronic cough may provide opportunities to reduce the associated burden for patients and healthcare systems.Springer New YorkUniversitat Autònoma de Barcelona 22023-01-0120232023-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/280824https://dx.doi.org/urn:doi:10.1007/s00408-023-00620-yreponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2808242026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain A Retrospective Multicenter Study |
| title |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| spellingShingle |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain Domingo, Christian|||0000-0001-8358-773X Health resource utilization Noninterventional study Refractory chronic cough Spain Unexplained chronic cough |
| title_short |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| title_full |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| title_fullStr |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| title_full_unstemmed |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| title_sort |
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain |
| dc.creator.none.fl_str_mv |
Domingo, Christian|||0000-0001-8358-773X Dávila, Ignacio|||0000-0001-8485-5513 Puente, Luis|||0000-0001-8501-0117 Quirce Gancedo, Santiago|||0000-0001-8086-0921 Arismendi, Ebymar|||0000-0002-7749-2838 Díaz Palacios, Miguel Pereira-Vega, Antonio|||0000-0002-6281-4793 De Diego, Alfredo Rodriguez Hermosa, Juan Luis|||0000-0003-0552-2484 Cea-Calvo, Luis Sánchez-Jareño, Marta López Cotarelo, Pilar |
| author |
Domingo, Christian|||0000-0001-8358-773X |
| author_facet |
Domingo, Christian|||0000-0001-8358-773X Dávila, Ignacio|||0000-0001-8485-5513 Puente, Luis|||0000-0001-8501-0117 Quirce Gancedo, Santiago|||0000-0001-8086-0921 Arismendi, Ebymar|||0000-0002-7749-2838 Díaz Palacios, Miguel Pereira-Vega, Antonio|||0000-0002-6281-4793 De Diego, Alfredo Rodriguez Hermosa, Juan Luis|||0000-0003-0552-2484 Cea-Calvo, Luis Sánchez-Jareño, Marta López Cotarelo, Pilar |
| author_role |
author |
| author2 |
Dávila, Ignacio|||0000-0001-8485-5513 Puente, Luis|||0000-0001-8501-0117 Quirce Gancedo, Santiago|||0000-0001-8086-0921 Arismendi, Ebymar|||0000-0002-7749-2838 Díaz Palacios, Miguel Pereira-Vega, Antonio|||0000-0002-6281-4793 De Diego, Alfredo Rodriguez Hermosa, Juan Luis|||0000-0003-0552-2484 Cea-Calvo, Luis Sánchez-Jareño, Marta López Cotarelo, Pilar |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
Health resource utilization Noninterventional study Refractory chronic cough Spain Unexplained chronic cough |
| topic |
Health resource utilization Noninterventional study Refractory chronic cough Spain Unexplained chronic cough |
| description |
Purpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are challenging to diagnose and manage, with substantial economic implications for healthcare systems. Methods: This retrospective multicenter non-interventional study aimed to characterize the profile and health resource consumption of patients with RCC or UCC who attended outpatient clinics at Spanish hospitals. Data were collected from medical records of patients with RCC or UCC for up to 3 years before study inclusion. Results: The patient cohort (n = 196) was representative of the chronic cough population (77.6% female, mean age 58.5 years). Two-thirds of patients (n = 126) had RCC. The most frequently visited doctors were pulmonologists (93.4% of patients) and primary care physicians (78.6%), with a mean of 5 visits per patient over three years' observation. The most common diagnostic tests were chest x-ray (83.7%) and spirometry with bronchodilation (77.0%). The most commonly prescribed treatments were proton pump inhibitors (79.6%) and respiratory medications (87.8%). Antibiotics were prescribed empirically to 56 (28.6%) patients. Differences between RCC or UCC groups related mainly to approaches used to manage cough-associated conditions (gastroesophageal reflux disease, asthma) in patients with RCC. Conclusion: RCC and UCC are responsible for high health resource utilization in Spanish hospitals. Specific treatments targeting the pathological processes driving chronic cough may provide opportunities to reduce the associated burden for patients and healthcare systems. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2 2023-01-01 2023 2023-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/280824 https://dx.doi.org/urn:doi:10.1007/s00408-023-00620-y |
| url |
https://ddd.uab.cat/record/280824 https://dx.doi.org/urn:doi:10.1007/s00408-023-00620-y |
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Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Springer New York |
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Springer New York |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Universitat Autònoma de Barcelona |
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Dipòsit Digital de Documents de la UAB |
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