Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates

Commercial pure titanium is known as good substitute for cortical bone tissue. Nevertheless, stress-shielding and the lack of osseointegration are still some limitations to solve. In this study, porous titanium substrates were manufactured by space-holder technique (50 vol% of NH4HCO3 with particle...

Full description

Bibliographic Details
Authors: Domínguez Trujillo, Cristina, Ternero Fernández, Fátima, Rodríguez Ortiz, José Antonio, Díaz Pavón, Juan José, Montealegre-Meléndez, Isabel, Arévalo Mora, Cristina María, García Moreno, Francisco, Torres Hernández, Yadir
Format: article
Status:Versión aceptada para publicación
Publication Date:2018
Country:España
Institution:Universidad de Sevilla (US)
Repository:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/154934
Online Access:https://hdl.handle.net/11441/154934
https://doi.org/10.1016/j.surfcoat.2018.01.019
Access Level:Open access
Keyword:Porous titanium
Stress shielding
Bioglass® coating
Hydroxyapatite
In vitro bioactivity
id ES_ab86987dd92c2eeea107de834c0d4d5f
oai_identifier_str oai:idus.us.es:11441/154934
network_acronym_str ES
network_name_str España
repository_id_str
spelling Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substratesDomínguez Trujillo, CristinaTernero Fernández, FátimaRodríguez Ortiz, José AntonioDíaz Pavón, Juan JoséMontealegre-Meléndez, IsabelArévalo Mora, Cristina MaríaGarcía Moreno, FranciscoTorres Hernández, YadirPorous titaniumStress shieldingBioglass® coatingHydroxyapatiteIn vitro bioactivityCommercial pure titanium is known as good substitute for cortical bone tissue. Nevertheless, stress-shielding and the lack of osseointegration are still some limitations to solve. In this study, porous titanium substrates were manufactured by space-holder technique (50 vol% of NH4HCO3 with particle size between 250 and 355 μm). The obtained stiffness and yield strength of specimens were compatible with cortical bone tissue. The substrates were coated with three layers of Bioglass® 45S5 (BG) by dripping sedimentation, a new and economic technique. The porosity and surface characterization were performed by Archimedes' method, image analysis, X-ray micro computed tomography and confocal laser microscopy, while the mechanical behavior was analyzed by ultrasound technique, uniaxial compression and micro-mechanical testing. Homogeneity, infiltration efficiency and coating integrity were evaluated. The adhesion of the coating was better on porous titanium substrates than on full dense ones. Finally, the bioactivity of the BG coating was determined via immersion in Simulated Body Fluid. The formation and growth of hydroxyapatite on the substrate were studied by scanning electron microscopy and X-ray diffraction analysis. The results showed hydroxyapatite formation in both coated full dense and porous samples. These features indicate the improvement of osseointegration for this sort of load bearing Ti implantsElsevierIngeniería y Ciencia de los Materiales y del TransporteTEP123: Metalurgia e Ingeniería de los MaterialesJunta de AndalucíaEuropean Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)Ministerio de Economia, Industria y Competitividad (MINECO). España2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/154934https://doi.org/10.1016/j.surfcoat.2018.01.019reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésSurface and Coatings Technology, 338, 32-37.P12-TEP-1401MAT2015-71284-Phttps://www.sciencedirect.com/science/article/pii/S0257897218300276info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1549342026-06-17T12:51:07Z
dc.title.none.fl_str_mv Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
title Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
spellingShingle Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
Domínguez Trujillo, Cristina
Porous titanium
Stress shielding
Bioglass® coating
Hydroxyapatite
In vitro bioactivity
title_short Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
title_full Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
title_fullStr Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
title_full_unstemmed Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
title_sort Improvement of the balance between a reduced stress shielding and bone ingrowth by bioactive coatings onto porous titanium substrates
dc.creator.none.fl_str_mv Domínguez Trujillo, Cristina
Ternero Fernández, Fátima
Rodríguez Ortiz, José Antonio
Díaz Pavón, Juan José
Montealegre-Meléndez, Isabel
Arévalo Mora, Cristina María
García Moreno, Francisco
Torres Hernández, Yadir
author Domínguez Trujillo, Cristina
author_facet Domínguez Trujillo, Cristina
Ternero Fernández, Fátima
Rodríguez Ortiz, José Antonio
Díaz Pavón, Juan José
Montealegre-Meléndez, Isabel
Arévalo Mora, Cristina María
García Moreno, Francisco
Torres Hernández, Yadir
author_role author
author2 Ternero Fernández, Fátima
Rodríguez Ortiz, José Antonio
Díaz Pavón, Juan José
Montealegre-Meléndez, Isabel
Arévalo Mora, Cristina María
García Moreno, Francisco
Torres Hernández, Yadir
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ingeniería y Ciencia de los Materiales y del Transporte
TEP123: Metalurgia e Ingeniería de los Materiales
Junta de Andalucía
European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)
Ministerio de Economia, Industria y Competitividad (MINECO). España
dc.subject.none.fl_str_mv Porous titanium
Stress shielding
Bioglass® coating
Hydroxyapatite
In vitro bioactivity
topic Porous titanium
Stress shielding
Bioglass® coating
Hydroxyapatite
In vitro bioactivity
description Commercial pure titanium is known as good substitute for cortical bone tissue. Nevertheless, stress-shielding and the lack of osseointegration are still some limitations to solve. In this study, porous titanium substrates were manufactured by space-holder technique (50 vol% of NH4HCO3 with particle size between 250 and 355 μm). The obtained stiffness and yield strength of specimens were compatible with cortical bone tissue. The substrates were coated with three layers of Bioglass® 45S5 (BG) by dripping sedimentation, a new and economic technique. The porosity and surface characterization were performed by Archimedes' method, image analysis, X-ray micro computed tomography and confocal laser microscopy, while the mechanical behavior was analyzed by ultrasound technique, uniaxial compression and micro-mechanical testing. Homogeneity, infiltration efficiency and coating integrity were evaluated. The adhesion of the coating was better on porous titanium substrates than on full dense ones. Finally, the bioactivity of the BG coating was determined via immersion in Simulated Body Fluid. The formation and growth of hydroxyapatite on the substrate were studied by scanning electron microscopy and X-ray diffraction analysis. The results showed hydroxyapatite formation in both coated full dense and porous samples. These features indicate the improvement of osseointegration for this sort of load bearing Ti implants
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/154934
https://doi.org/10.1016/j.surfcoat.2018.01.019
url https://hdl.handle.net/11441/154934
https://doi.org/10.1016/j.surfcoat.2018.01.019
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Surface and Coatings Technology, 338, 32-37.
P12-TEP-1401
MAT2015-71284-P
https://www.sciencedirect.com/science/article/pii/S0257897218300276
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416277054849024
score 15,301603

Similar Items