Private versus social incentives for pharmaceutical innovation

We provide a theoretical framework to contribute to the current debate regarding the tendency of pharmaceutical companies to direct their R&D toward marketing products that are follow-on drugs of already existing drugs, rather than toward the development of breakthrough drugs. We construct a mod...

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Detalles Bibliográficos
Autores: González, Paula, Macho Stadler, Inés|||0000-0002-2415-7972, Pérez Castrillo, David|||0000-0002-1840-7621
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:171141
Acceso en línea:https://ddd.uab.cat/record/171141
https://dx.doi.org/urn:doi:10.1016/j.jhealeco.2015.12.003
Access Level:acceso abierto
Palabra clave:Pharmaceuticals
R&D activities
Me-too drugs
Breakthrough drugs
Incremental innovation
Radical innovation
Descripción
Sumario:We provide a theoretical framework to contribute to the current debate regarding the tendency of pharmaceutical companies to direct their R&D toward marketing products that are follow-on drugs of already existing drugs, rather than toward the development of breakthrough drugs. We construct a model with a population of patients who can be treated with drugs that are horizontally and vertically differentiated. In addition to a pioneering drug, a new drug can be marketed as the result of an innovative process. We analyze physician prescription choices and the optimal pricing decision of an innovative firm. We also characterize the incentives of the innovative firm to conduct R&D activities, disentangling the quest for breakthrough drugs from the firm effort to develop follow-on drugs. Our results offer theoretical support for the conventional wisdom that pharmaceutical firms devote too many resources to conducting R&D activities that lead to incremental innovations.