The gut microbiome in pregnancy and pregnancy complications

During gestation, the female body undergoes a number of changes; accordingly, her microbiota also undergoes marked changes throughout the duration of her pregnancy. Some shifts in the microbial community are imprinted even before pregnancy and may affect a woman's ability to conceive. Prepregna...

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Detalles Bibliográficos
Autores: Turjeman, Sondra, Collado, María Carmen, Koren, Omry
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/240496
Acceso en línea:http://hdl.handle.net/10261/240496
Access Level:acceso abierto
Palabra clave:Microbiome
Pregnancy
Gestational diabetes
Preeclampsia
Descripción
Sumario:During gestation, the female body undergoes a number of changes; accordingly, her microbiota also undergoes marked changes throughout the duration of her pregnancy. Some shifts in the microbial community are imprinted even before pregnancy and may affect a woman's ability to conceive. Prepregnancy obesity and inflammatory bowel disease are associated with gestational dysbiosis, as are several conditions occurring during pregnancy, including gestational diabetes mellitus and preeclampsia. Here, we review pregnancy and associated complications in the context of the gut microbiota, but dysbiosis in other microbial communities, including those of the vagina, oral cavity, and cervix, is also associated with pregnancy-related conditions. We not only highlight the numerous studies conducted thus far but also discuss some of the shortcomings in the field and provide important directions for future research.