Inorganic Pyrophosphatases: Study of Interest
Inorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble p...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Universidad de Sevilla (US) |
| Repositorio: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:idus.us.es:11441/85284 |
| Acceso en línea: | https://hdl.handle.net/11441/85284 https://doi.org/10.4236/abb.2017.810028 |
| Access Level: | acceso abierto |
| Palabra clave: | Pyrophosphatases Structure Catalytic Activity Phylogeny Pathology |
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Inorganic Pyrophosphatases: Study of InterestPapa Daouda, MarElkhalfi, BouchraPérez Castiñeira, José RománSerrano Delgado, AurelioSoukri, AbdelazizPyrophosphatasesStructureCatalytic ActivityPhylogenyPathologyInorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble pyrophosphatases are ubiquitous enzymes and play a key role in regulating the rate of pyrophosphate and balance in this sense, the biosynthetic reactions. Membrane pyrophosphatases are ion pumps, producing a proton or sodium gradient, and provide critical energy reserves to organisms, especially during stress conditions. Several studies have shown that these enzymes are involved in numerous disorders (diseases, fault cell growth∙∙∙). However they are potential targets for the development of agents against parasites. This article consists of a description of the different types, structures, catalytic properties of inorganic pyrophosphatases and their involvement in cellular metabolism.Scientific Research PublishingBioquímica Vegetal y Biología Molecular2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/85284https://doi.org/10.4236/abb.2017.810028reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésAdvances in Bioscience and Biotechnology, 8, 388-397.https://doi.org/10.4236/abb.2017.810028info:eu-repo/semantics/openAccessoai:idus.us.es:11441/852842026-06-17T12:51:07Z |
| dc.title.none.fl_str_mv |
Inorganic Pyrophosphatases: Study of Interest |
| title |
Inorganic Pyrophosphatases: Study of Interest |
| spellingShingle |
Inorganic Pyrophosphatases: Study of Interest Papa Daouda, Mar Pyrophosphatases Structure Catalytic Activity Phylogeny Pathology |
| title_short |
Inorganic Pyrophosphatases: Study of Interest |
| title_full |
Inorganic Pyrophosphatases: Study of Interest |
| title_fullStr |
Inorganic Pyrophosphatases: Study of Interest |
| title_full_unstemmed |
Inorganic Pyrophosphatases: Study of Interest |
| title_sort |
Inorganic Pyrophosphatases: Study of Interest |
| dc.creator.none.fl_str_mv |
Papa Daouda, Mar Elkhalfi, Bouchra Pérez Castiñeira, José Román Serrano Delgado, Aurelio Soukri, Abdelaziz |
| author |
Papa Daouda, Mar |
| author_facet |
Papa Daouda, Mar Elkhalfi, Bouchra Pérez Castiñeira, José Román Serrano Delgado, Aurelio Soukri, Abdelaziz |
| author_role |
author |
| author2 |
Elkhalfi, Bouchra Pérez Castiñeira, José Román Serrano Delgado, Aurelio Soukri, Abdelaziz |
| author2_role |
author author author author |
| dc.contributor.none.fl_str_mv |
Bioquímica Vegetal y Biología Molecular |
| dc.subject.none.fl_str_mv |
Pyrophosphatases Structure Catalytic Activity Phylogeny Pathology |
| topic |
Pyrophosphatases Structure Catalytic Activity Phylogeny Pathology |
| description |
Inorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble pyrophosphatases are ubiquitous enzymes and play a key role in regulating the rate of pyrophosphate and balance in this sense, the biosynthetic reactions. Membrane pyrophosphatases are ion pumps, producing a proton or sodium gradient, and provide critical energy reserves to organisms, especially during stress conditions. Several studies have shown that these enzymes are involved in numerous disorders (diseases, fault cell growth∙∙∙). However they are potential targets for the development of agents against parasites. This article consists of a description of the different types, structures, catalytic properties of inorganic pyrophosphatases and their involvement in cellular metabolism. |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/11441/85284 https://doi.org/10.4236/abb.2017.810028 |
| url |
https://hdl.handle.net/11441/85284 https://doi.org/10.4236/abb.2017.810028 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Advances in Bioscience and Biotechnology, 8, 388-397. https://doi.org/10.4236/abb.2017.810028 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf application/pdf |
| dc.publisher.none.fl_str_mv |
Scientific Research Publishing |
| publisher.none.fl_str_mv |
Scientific Research Publishing |
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reponame:idUS. Depósito de Investigación de la Universidad de Sevilla instname:Universidad de Sevilla (US) |
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Universidad de Sevilla (US) |
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idUS. Depósito de Investigación de la Universidad de Sevilla |
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idUS. Depósito de Investigación de la Universidad de Sevilla |
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15.300719 |