Inorganic Pyrophosphatases: Study of Interest

Inorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble p...

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Detalles Bibliográficos
Autores: Papa Daouda, Mar, Elkhalfi, Bouchra, Pérez Castiñeira, José Román, Serrano Delgado, Aurelio, Soukri, Abdelaziz
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/85284
Acceso en línea:https://hdl.handle.net/11441/85284
https://doi.org/10.4236/abb.2017.810028
Access Level:acceso abierto
Palabra clave:Pyrophosphatases
Structure
Catalytic Activity
Phylogeny
Pathology
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spelling Inorganic Pyrophosphatases: Study of InterestPapa Daouda, MarElkhalfi, BouchraPérez Castiñeira, José RománSerrano Delgado, AurelioSoukri, AbdelazizPyrophosphatasesStructureCatalytic ActivityPhylogenyPathologyInorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble pyrophosphatases are ubiquitous enzymes and play a key role in regulating the rate of pyrophosphate and balance in this sense, the biosynthetic reactions. Membrane pyrophosphatases are ion pumps, producing a proton or sodium gradient, and provide critical energy reserves to organisms, especially during stress conditions. Several studies have shown that these enzymes are involved in numerous disorders (diseases, fault cell growth∙∙∙). However they are potential targets for the development of agents against parasites. This article consists of a description of the different types, structures, catalytic properties of inorganic pyrophosphatases and their involvement in cellular metabolism.Scientific Research PublishingBioquímica Vegetal y Biología Molecular2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/85284https://doi.org/10.4236/abb.2017.810028reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésAdvances in Bioscience and Biotechnology, 8, 388-397.https://doi.org/10.4236/abb.2017.810028info:eu-repo/semantics/openAccessoai:idus.us.es:11441/852842026-06-17T12:51:07Z
dc.title.none.fl_str_mv Inorganic Pyrophosphatases: Study of Interest
title Inorganic Pyrophosphatases: Study of Interest
spellingShingle Inorganic Pyrophosphatases: Study of Interest
Papa Daouda, Mar
Pyrophosphatases
Structure
Catalytic Activity
Phylogeny
Pathology
title_short Inorganic Pyrophosphatases: Study of Interest
title_full Inorganic Pyrophosphatases: Study of Interest
title_fullStr Inorganic Pyrophosphatases: Study of Interest
title_full_unstemmed Inorganic Pyrophosphatases: Study of Interest
title_sort Inorganic Pyrophosphatases: Study of Interest
dc.creator.none.fl_str_mv Papa Daouda, Mar
Elkhalfi, Bouchra
Pérez Castiñeira, José Román
Serrano Delgado, Aurelio
Soukri, Abdelaziz
author Papa Daouda, Mar
author_facet Papa Daouda, Mar
Elkhalfi, Bouchra
Pérez Castiñeira, José Román
Serrano Delgado, Aurelio
Soukri, Abdelaziz
author_role author
author2 Elkhalfi, Bouchra
Pérez Castiñeira, José Román
Serrano Delgado, Aurelio
Soukri, Abdelaziz
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Bioquímica Vegetal y Biología Molecular
dc.subject.none.fl_str_mv Pyrophosphatases
Structure
Catalytic Activity
Phylogeny
Pathology
topic Pyrophosphatases
Structure
Catalytic Activity
Phylogeny
Pathology
description Inorganic pyrophosphatases are enzymes that catalyze the hydrolysis of inorganic pyrophosphate to orthophosphate. These enzymes are divided into two groups: the soluble pyrophosphatases and the membrane pyrophosphatases. They vary in structure and each has a determined catalysis mechanism. Soluble pyrophosphatases are ubiquitous enzymes and play a key role in regulating the rate of pyrophosphate and balance in this sense, the biosynthetic reactions. Membrane pyrophosphatases are ion pumps, producing a proton or sodium gradient, and provide critical energy reserves to organisms, especially during stress conditions. Several studies have shown that these enzymes are involved in numerous disorders (diseases, fault cell growth∙∙∙). However they are potential targets for the development of agents against parasites. This article consists of a description of the different types, structures, catalytic properties of inorganic pyrophosphatases and their involvement in cellular metabolism.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/85284
https://doi.org/10.4236/abb.2017.810028
url https://hdl.handle.net/11441/85284
https://doi.org/10.4236/abb.2017.810028
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Advances in Bioscience and Biotechnology, 8, 388-397.
https://doi.org/10.4236/abb.2017.810028
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scientific Research Publishing
publisher.none.fl_str_mv Scientific Research Publishing
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
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