Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial

Background In the predictD-intervention. GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%. although the results were not statistically significant. Aim To determine whether the predictD-intervention is effective at preve...

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Autores: Moreno-Peral, P, Conejo-Ceron, S, Luna, JD, King, M, Nazareth, I, Martin-Perez, C, Fernandez-Alonso, C, Ballesta-Rodriguez, MI, Fernandez, A, Aiarzaguena, JM, Monton-Franco, C, Bellon, JA
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Universidad de Zaragoza
Repositório:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:151977
Acesso em linha:http://zaguan.unizar.es/record/151977
Access Level:Acceso aberto
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spelling Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trialMoreno-Peral, PConejo-Ceron, SLuna, JDKing, MNazareth, IMartin-Perez, CFernandez-Alonso, CBallesta-Rodriguez, MIFernandez, AAiarzaguena, JMMonton-Franco, CBellon, JABackground In the predictD-intervention. GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%. although the results were not statistically significant. Aim To determine whether the predictD-intervention is effective at preventing anxiety in primary cam patients without depression or anxiety. Design and setting Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012. Method In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26-27 eligible patients for each GP The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months. Results A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients. 2597 (86.6%) were evaluated at the end of the study. At 18 months. lac.% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI =11.4% to 14.8%) in the usual-care group (absolute difference = -2.7%195% CI = -5.1% to -0.3%1; P=0.029). Conclusion A personalised intervention delivered by the prevention of depression prrmded a ; but statistically significant reduction in the incidence of anxiety2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/151977reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/grantAgreement/ES/ISCIII/PI12-02755info:eu-repo/grantAgreement/ES/ISCIII/PS09-00461info:eu-repo/grantAgreement/ES/ISCIII/PS09-00849info:eu-repo/grantAgreement/ES/ISCIII/PS09-01095info:eu-repo/grantAgreement/ES/ISCIII/PS09-02147info:eu-repo/grantAgreement/ES/ISCIII/PS09-02272info:eu-repo/semantics/openAccessoai:zaguan.unizar.es:1519772026-05-29T13:59:51Z
dc.title.none.fl_str_mv Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
title Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
spellingShingle Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
Moreno-Peral, P
title_short Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
title_full Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
title_fullStr Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
title_full_unstemmed Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
title_sort Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial
dc.creator.none.fl_str_mv Moreno-Peral, P
Conejo-Ceron, S
Luna, JD
King, M
Nazareth, I
Martin-Perez, C
Fernandez-Alonso, C
Ballesta-Rodriguez, MI
Fernandez, A
Aiarzaguena, JM
Monton-Franco, C
Bellon, JA
author Moreno-Peral, P
author_facet Moreno-Peral, P
Conejo-Ceron, S
Luna, JD
King, M
Nazareth, I
Martin-Perez, C
Fernandez-Alonso, C
Ballesta-Rodriguez, MI
Fernandez, A
Aiarzaguena, JM
Monton-Franco, C
Bellon, JA
author_role author
author2 Conejo-Ceron, S
Luna, JD
King, M
Nazareth, I
Martin-Perez, C
Fernandez-Alonso, C
Ballesta-Rodriguez, MI
Fernandez, A
Aiarzaguena, JM
Monton-Franco, C
Bellon, JA
author2_role author
author
author
author
author
author
author
author
author
author
author
description Background In the predictD-intervention. GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%. although the results were not statistically significant. Aim To determine whether the predictD-intervention is effective at preventing anxiety in primary cam patients without depression or anxiety. Design and setting Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012. Method In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26-27 eligible patients for each GP The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months. Results A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients. 2597 (86.6%) were evaluated at the end of the study. At 18 months. lac.% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI =11.4% to 14.8%) in the usual-care group (absolute difference = -2.7%195% CI = -5.1% to -0.3%1; P=0.029). Conclusion A personalised intervention delivered by the prevention of depression prrmded a ; but statistically significant reduction in the incidence of anxiety
publishDate 2021
dc.date.none.fl_str_mv 2021
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dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
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info:eu-repo/grantAgreement/ES/ISCIII/PS09-02147
info:eu-repo/grantAgreement/ES/ISCIII/PS09-02272
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eu_rights_str_mv openAccess
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instname_str Universidad de Zaragoza
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