Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort
Childhood obesity is a growing public health concern increasingly linked to gut microbiota. We analysed associations between microbiota composition, functionality, and weight status in 1134 children aged 3-6 years from the CORALS cohort.
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2026 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/419367 |
| Acesso em linha: | http://hdl.handle.net/10261/419367 https://api.elsevier.com/content/abstract/scopus_id/105029569356 |
| Access Level: | acceso abierto |
| Palavra-chave: | Childhood obesity Childhood obesity risk assessment study - CORALS Enterotypes Gut microbiota Metabolic pathways children obesity risk assessment microbiomes |
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Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohortVázquez-Bolea, NataliaMora-Martínez, CarlosCuervo, MartaMartinez, J AlfredoGil-Campos, MercedesLeis, RosauraBabio, NancyMoreno, Luis A.Corella, DoloresMoreira Echeverria, AnaAguilera, Concepción M.Castro Collado, CristinaPicáns Leis, RosauraHernández-Cacho, AdriánMiguel-Berges, Maria L.Martin Climent, PaulaJurado Castro, Jose ManuelVázquez Cobela, RocíoPlaza Diaz, JulioRueda-De Torre, IsabelPastor Villaescusa, Belénde la Torre Aguilar, Maria JoséSalas Salvadó, JordiSanz Herranz, YolandaNavas Carretero, SantiagoChildhood obesityChildhood obesity risk assessment study - CORALSEnterotypesGut microbiotaMetabolic pathwayschildrenobesityrisk assessmentmicrobiomesChildhood obesity is a growing public health concern increasingly linked to gut microbiota. We analysed associations between microbiota composition, functionality, and weight status in 1134 children aged 3-6 years from the CORALS cohort.Funds for the establishment of the CORALS cohort in the first year of the study (2019) were provided by an agreement between the Danone Institute from Spain and the CIBEROBN. This study was supported by the EIT-FOOD co-founded by the EU (Climb-Out project; Ref EIT21249), the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI grant, Ref: PID2023-150693OB-I00)), the Generalitat Valenciana (PROMETEO21/2021) and the award to IATA-CSIC as an Accredited Research Center of Excellence “Severo Ochoa” (CEX2021-001189-S/MCIN/AEI/10.13039/501100011033). A partial grant for Navarra was provided by the Department of Education of the Government of Navarra (0000-RES1-2020-000338). This research was supported by an FPU grant from the Spanish Ministry of Science, Innovation and Universities (MCIU) to Natalia Vázquez-Bolea (FPU23/01950).With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2021-001189-S).Peer reviewedElsevierAgencia Estatal de Investigación (España)Ministerio de Ciencia e Innovación (España)European CommissionMinisterio de Ciencia, Innovación y Universidades (España)Generalitat ValencianaDiputación Foral de NavarraConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262026info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/419367https://api.elsevier.com/content/abstract/scopus_id/105029569356reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/CEX2021-001189-Sinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-150693OB-I00Clinical nutrition (Edinburgh, Scotland)The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1016/j.clnu.2025.106558https://doi.org/10.1016/j.clnu.2025.106558Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4193672026-05-22T06:33:51Z |
| dc.title.none.fl_str_mv |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| title |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| spellingShingle |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort Vázquez-Bolea, Natalia Childhood obesity Childhood obesity risk assessment study - CORALS Enterotypes Gut microbiota Metabolic pathways children obesity risk assessment microbiomes |
| title_short |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| title_full |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| title_fullStr |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| title_full_unstemmed |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| title_sort |
Gut microbiota composition and derived enterotypes are associated with ponderal status in preschool children. Childhood obesity risk assessment longitudinal study (CORALS) cohort |
| dc.creator.none.fl_str_mv |
Vázquez-Bolea, Natalia Mora-Martínez, Carlos Cuervo, Marta Martinez, J Alfredo Gil-Campos, Mercedes Leis, Rosaura Babio, Nancy Moreno, Luis A. Corella, Dolores Moreira Echeverria, Ana Aguilera, Concepción M. Castro Collado, Cristina Picáns Leis, Rosaura Hernández-Cacho, Adrián Miguel-Berges, Maria L. Martin Climent, Paula Jurado Castro, Jose Manuel Vázquez Cobela, Rocío Plaza Diaz, Julio Rueda-De Torre, Isabel Pastor Villaescusa, Belén de la Torre Aguilar, Maria José Salas Salvadó, Jordi Sanz Herranz, Yolanda Navas Carretero, Santiago |
| author |
Vázquez-Bolea, Natalia |
| author_facet |
Vázquez-Bolea, Natalia Mora-Martínez, Carlos Cuervo, Marta Martinez, J Alfredo Gil-Campos, Mercedes Leis, Rosaura Babio, Nancy Moreno, Luis A. Corella, Dolores Moreira Echeverria, Ana Aguilera, Concepción M. Castro Collado, Cristina Picáns Leis, Rosaura Hernández-Cacho, Adrián Miguel-Berges, Maria L. Martin Climent, Paula Jurado Castro, Jose Manuel Vázquez Cobela, Rocío Plaza Diaz, Julio Rueda-De Torre, Isabel Pastor Villaescusa, Belén de la Torre Aguilar, Maria José Salas Salvadó, Jordi Sanz Herranz, Yolanda Navas Carretero, Santiago |
| author_role |
author |
| author2 |
Mora-Martínez, Carlos Cuervo, Marta Martinez, J Alfredo Gil-Campos, Mercedes Leis, Rosaura Babio, Nancy Moreno, Luis A. Corella, Dolores Moreira Echeverria, Ana Aguilera, Concepción M. Castro Collado, Cristina Picáns Leis, Rosaura Hernández-Cacho, Adrián Miguel-Berges, Maria L. Martin Climent, Paula Jurado Castro, Jose Manuel Vázquez Cobela, Rocío Plaza Diaz, Julio Rueda-De Torre, Isabel Pastor Villaescusa, Belén de la Torre Aguilar, Maria José Salas Salvadó, Jordi Sanz Herranz, Yolanda Navas Carretero, Santiago |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Agencia Estatal de Investigación (España) Ministerio de Ciencia e Innovación (España) European Commission Ministerio de Ciencia, Innovación y Universidades (España) Generalitat Valenciana Diputación Foral de Navarra Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Childhood obesity Childhood obesity risk assessment study - CORALS Enterotypes Gut microbiota Metabolic pathways children obesity risk assessment microbiomes |
| topic |
Childhood obesity Childhood obesity risk assessment study - CORALS Enterotypes Gut microbiota Metabolic pathways children obesity risk assessment microbiomes |
| description |
Childhood obesity is a growing public health concern increasingly linked to gut microbiota. We analysed associations between microbiota composition, functionality, and weight status in 1134 children aged 3-6 years from the CORALS cohort. |
| publishDate |
2026 |
| dc.date.none.fl_str_mv |
2026 2026 2026 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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http://hdl.handle.net/10261/419367 https://api.elsevier.com/content/abstract/scopus_id/105029569356 |
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http://hdl.handle.net/10261/419367 https://api.elsevier.com/content/abstract/scopus_id/105029569356 |
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Inglés |
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Inglés |
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#PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/CEX2021-001189-S info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-150693OB-I00 Clinical nutrition (Edinburgh, Scotland) The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1016/j.clnu.2025.106558 https://doi.org/10.1016/j.clnu.2025.106558 Sí |
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