Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Detalles Bibliográficos
Autores: Zoco de la Fuente, Aitana, García-García, Ane, Pérez-Álvarez, Leyre, Moreno-Benítez, Isabel, Larrea, Asier, Martín, César, Vilas-Vilela, José Luis
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/362268
Acceso en línea:http://hdl.handle.net/10261/362268
Access Level:acceso abierto
Palabra clave:Methacrylated alginate
Photo-cross-linking
Extrusion printing
id ES_aab653b48d2a2740da8e6845a9500a28
oai_identifier_str oai:digital.csic.es:10261/362268
network_acronym_str ES
network_name_str España
repository_id_str
spelling Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D PrintingZoco de la Fuente, AitanaGarcía-García, AnePérez-Álvarez, LeyreMoreno-Benítez, IsabelLarrea, AsierMartín, CésarVilas-Vilela, José LuisMethacrylated alginatePhoto-cross-linkingExtrusion printing© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Naturally derived biopolymers modifying or combining with other components are excellent candidates to promote the full potential of additive manufacturing in biomedicine, cosmetics, and the food industry. This work aims to develop new photo-cross-linkable alginate-based inks for extrusion 3D printing. Specifically, this work is focused on the effect of the addition of cross-linkers with different chemical structures (polyethylene glycol diacrylate (PEGDA), N,N′-methylenebisacrylamide (NMBA), and acrylic acid (AA)) in the potential printability and physical properties of methacrylated alginate (AlgMe) hydrogels. Although all inks showed maximum photo-curing conversions and gelation times less than 2 min, only those structures printed with the inks incorporating cross-linking agents with flexible and long chain structure (PEGDA and AA) displayed acceptable size accuracy (~0.4–0.5) and printing index (Pr ~1.00). The addition of these cross-linking agents leads to higher Young’s moduli (from 1.6 to 2.0–2.6 KPa) in the hydrogels, and their different chemical structures results in variations in their mechanical and rheological properties. However, similar swelling ability (~15 swelling factor), degradability (~45 days 100% weight loss), and cytocompatibility (~100%) were assessed in all the systems, which is of great importance for the final applicability of these hydrogels.This research was funded by the Basque government (ELKARTEK), grant KK-2023/00056, Grupos Consolidados (IT1756-22), and the Ministry of Science and Innovation, grant PID2022-138572OB-C42, and PID2022-136788OB-I00.Peer reviewedMultidisciplinary Digital Publishing InstituteEusko JaurlaritzaMinisterio de Ciencia e Innovación (España)Agencia Estatal de Investigación (España)Larrea, Asier [0000-0001-9107-4299]Martín, César [0000-0002-4087-8729]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242024info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/362268reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-138572OB-C42info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-136788OB-I00https://doi.org/10.3390/polym16070986Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3622682026-05-22T06:33:51Z
dc.title.none.fl_str_mv Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
title Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
spellingShingle Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
Zoco de la Fuente, Aitana
Methacrylated alginate
Photo-cross-linking
Extrusion printing
title_short Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
title_full Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
title_fullStr Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
title_full_unstemmed Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
title_sort Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
dc.creator.none.fl_str_mv Zoco de la Fuente, Aitana
García-García, Ane
Pérez-Álvarez, Leyre
Moreno-Benítez, Isabel
Larrea, Asier
Martín, César
Vilas-Vilela, José Luis
author Zoco de la Fuente, Aitana
author_facet Zoco de la Fuente, Aitana
García-García, Ane
Pérez-Álvarez, Leyre
Moreno-Benítez, Isabel
Larrea, Asier
Martín, César
Vilas-Vilela, José Luis
author_role author
author2 García-García, Ane
Pérez-Álvarez, Leyre
Moreno-Benítez, Isabel
Larrea, Asier
Martín, César
Vilas-Vilela, José Luis
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Eusko Jaurlaritza
Ministerio de Ciencia e Innovación (España)
Agencia Estatal de Investigación (España)
Larrea, Asier [0000-0001-9107-4299]
Martín, César [0000-0002-4087-8729]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Methacrylated alginate
Photo-cross-linking
Extrusion printing
topic Methacrylated alginate
Photo-cross-linking
Extrusion printing
description © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/362268
url http://hdl.handle.net/10261/362268
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-138572OB-C42
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-136788OB-I00
https://doi.org/10.3390/polym16070986
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416205683523584
score 15,811543

Similares en LA Referencia