Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy
Cats can be carriers of infected arthropods and be infected with several vector-borne pathogens (VBP) but there is limited knowledge about their pathogenic role in cats. A cross-sectional controlled study investigated the clinical status and antibody (Bartonella henselae, Rickettsia conorii, Ehrlich...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:253470 |
| Acceso en línea: | https://ddd.uab.cat/record/253470 https://dx.doi.org/urn:doi:10.1186/s13071-018-2725-8 |
| Access Level: | acceso abierto |
| Palabra clave: | Cat Vector-borne pathogens Zoonosis Risk factor Ectoparasite Outdoor lifestyle Indoor lifestyle |
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Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern ItalyPersichetti, Maria FlaminiaPennisi, Maria Grazia|||0000-0002-3169-4194Vullo, AngelaMasucci, Marisa|||0000-0001-9893-4554Migliazzo, AntonellaSolano Gallego, Laia|||0000-0001-8479-4896CatVector-borne pathogensZoonosisRisk factorEctoparasiteOutdoor lifestyleIndoor lifestyleCats can be carriers of infected arthropods and be infected with several vector-borne pathogens (VBP) but there is limited knowledge about their pathogenic role in cats. A cross-sectional controlled study investigated the clinical status and antibody (Bartonella henselae, Rickettsia conorii, Ehrlichia canis, Anaplasma phagocytophilum, Babesia microti and Leishmania infantum) and/or blood PCR (Mycoplasma spp., Bartonella spp., Rickettsia spp., Ehrlichia/Anaplasma spp., piroplasmids, L. infantum, Hepatozoon felis) prevalence in 197 cats. Outdoor cats lacking ectoparasiticide treatment or hosting ectoparasites (study group [SG], n = 134) and indoor cats treated against ectoparasites (control group [CG], n = 63) were enrolled. Clinical data and retroviral co-infections were compared between the two groups. Multivariable analysis tested associations between variables and VBP exposure. Lymphadenia, stomatitis, and various haematological abnormalities were statistically more frequent in SG. Antibodies against R. conorii, B. henselae, A. phagocytophylum, B. microti, E. canis and L. infantum were detected. Bartonella henselae, Bartonella clarridgeiae, Mycoplasma haemofelis, " Candidatus Mycoplasma haemominutum" and " Candidatus Mycoplasma turicensis" DNA were identified. Very high antibody (87.8%) and PCR (40.1%) positivity to at least one pathogen were detected and were significantly higher in SG. Co-infections were confirmed in about one-third of the cats and were more frequent in SG cats. Molecular and overall (antibody and PCR) positivity to Bartonella and antibody positivity to R. conorii were higher in SG. Multivariable analysis found significant associations of Bartonella spp. infection with Feline Immunodeficiency Virus (FIV) infection and increased globulins, and of Mycoplasma spp. infection with adult age, FIV infection, anaemia, and increased creatinine. A very high prevalence of exposure to zoonotic VBP was found in cats, with Rickettsia and Bartonella infections being most prevalent. Some risk factors were documented namely for Mycoplasma spp. and Bartonella spp. The lifestyle of cats is clinically relevant and requires specific preventative measures to protect their health. The online version of this article (10.1186/s13071-018-2725-8) contains supplementary material, which is available to authorized users. 22018-01-0120182018-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/253470https://dx.doi.org/urn:doi:10.1186/s13071-018-2725-8reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2534702026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| title |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| spellingShingle |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy Persichetti, Maria Flaminia Cat Vector-borne pathogens Zoonosis Risk factor Ectoparasite Outdoor lifestyle Indoor lifestyle |
| title_short |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| title_full |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| title_fullStr |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| title_full_unstemmed |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| title_sort |
Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy |
| dc.creator.none.fl_str_mv |
Persichetti, Maria Flaminia Pennisi, Maria Grazia|||0000-0002-3169-4194 Vullo, Angela Masucci, Marisa|||0000-0001-9893-4554 Migliazzo, Antonella Solano Gallego, Laia|||0000-0001-8479-4896 |
| author |
Persichetti, Maria Flaminia |
| author_facet |
Persichetti, Maria Flaminia Pennisi, Maria Grazia|||0000-0002-3169-4194 Vullo, Angela Masucci, Marisa|||0000-0001-9893-4554 Migliazzo, Antonella Solano Gallego, Laia|||0000-0001-8479-4896 |
| author_role |
author |
| author2 |
Pennisi, Maria Grazia|||0000-0002-3169-4194 Vullo, Angela Masucci, Marisa|||0000-0001-9893-4554 Migliazzo, Antonella Solano Gallego, Laia|||0000-0001-8479-4896 |
| author2_role |
author author author author author |
| dc.subject.none.fl_str_mv |
Cat Vector-borne pathogens Zoonosis Risk factor Ectoparasite Outdoor lifestyle Indoor lifestyle |
| topic |
Cat Vector-borne pathogens Zoonosis Risk factor Ectoparasite Outdoor lifestyle Indoor lifestyle |
| description |
Cats can be carriers of infected arthropods and be infected with several vector-borne pathogens (VBP) but there is limited knowledge about their pathogenic role in cats. A cross-sectional controlled study investigated the clinical status and antibody (Bartonella henselae, Rickettsia conorii, Ehrlichia canis, Anaplasma phagocytophilum, Babesia microti and Leishmania infantum) and/or blood PCR (Mycoplasma spp., Bartonella spp., Rickettsia spp., Ehrlichia/Anaplasma spp., piroplasmids, L. infantum, Hepatozoon felis) prevalence in 197 cats. Outdoor cats lacking ectoparasiticide treatment or hosting ectoparasites (study group [SG], n = 134) and indoor cats treated against ectoparasites (control group [CG], n = 63) were enrolled. Clinical data and retroviral co-infections were compared between the two groups. Multivariable analysis tested associations between variables and VBP exposure. Lymphadenia, stomatitis, and various haematological abnormalities were statistically more frequent in SG. Antibodies against R. conorii, B. henselae, A. phagocytophylum, B. microti, E. canis and L. infantum were detected. Bartonella henselae, Bartonella clarridgeiae, Mycoplasma haemofelis, " Candidatus Mycoplasma haemominutum" and " Candidatus Mycoplasma turicensis" DNA were identified. Very high antibody (87.8%) and PCR (40.1%) positivity to at least one pathogen were detected and were significantly higher in SG. Co-infections were confirmed in about one-third of the cats and were more frequent in SG cats. Molecular and overall (antibody and PCR) positivity to Bartonella and antibody positivity to R. conorii were higher in SG. Multivariable analysis found significant associations of Bartonella spp. infection with Feline Immunodeficiency Virus (FIV) infection and increased globulins, and of Mycoplasma spp. infection with adult age, FIV infection, anaemia, and increased creatinine. A very high prevalence of exposure to zoonotic VBP was found in cats, with Rickettsia and Bartonella infections being most prevalent. Some risk factors were documented namely for Mycoplasma spp. and Bartonella spp. The lifestyle of cats is clinically relevant and requires specific preventative measures to protect their health. The online version of this article (10.1186/s13071-018-2725-8) contains supplementary material, which is available to authorized users. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2 2018-01-01 2018 2018-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/253470 https://dx.doi.org/urn:doi:10.1186/s13071-018-2725-8 |
| url |
https://ddd.uab.cat/record/253470 https://dx.doi.org/urn:doi:10.1186/s13071-018-2725-8 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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