Magnetic resonance volumetric quantification of vestibular endolymphatic hydrops in patients with unilateral definite meniere’s disease using 3D inversion recovery with real reconstruction (3D-REAL-IR) sequence

Background: The 3D-REAL-IR MRI sequence allows for an in vivo visualization of endolymphatic hydrops. Qualitative assessment methods of the severity of vestibular and cochlear hydrops are the most commonly used. Methods: A quantitative volumetric measurement of vestibular EH in patients with definit...

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Detalles Bibliográficos
Autores: Suarez-Vega, V. (Víctor)|||/items/fe8874b6-d093-4621-b1eb-fd8a5302fb92, Manrique-Huarte, R. (Raquel)|||/items/4e0d942c-9492-4896-8995-2d876c7cc3ff, Domínguez-Echávarri, P.D. (Pablo Daniel)|||/items/b70b7c2e-a8b5-40f0-bf39-569b3f7e07aa, Blanco-Pareja, M. (Melissa)|||/items/4af2d44e-82eb-4e42-8ae6-ff4aaaf230e1, Alonso-Burgos, A. (Alberto)|||/items/703e3f67-03f4-424c-9aba-e4cb858eb3ec, Perez-Fernandez, N. (Nicolás)|||/items/f35b1b73-f2d0-4c4c-9a3f-c496e4dff4d4
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/68708
Acceso en línea:https://hdl.handle.net/10171/68708
Access Level:acceso abierto
Palabra clave:Ménií¨re-™s disease
Endolymphatic hydrops
3D-REAL-IR
Vestibular endolymphatic ratio
Descripción
Sumario:Background: The 3D-REAL-IR MRI sequence allows for an in vivo visualization of endolymphatic hydrops. Qualitative assessment methods of the severity of vestibular and cochlear hydrops are the most commonly used. Methods: A quantitative volumetric measurement of vestibular EH in patients with definite unilateral Ménière’s disease using the 3D-REAL-IR sequence and the calculation of the endolymphatic ratio (ELR) was intended. Results: Volumetric calculations of the vestibules, vestibular endolymph and vestibular ELR are performed in 96 patients with unilateral Ménière’s disease and correlated with classic qualitative grading scales. Conclusions: Quantitative volumetric measurement of vestibular hydrops using the 3D-REAL-IR sequence is feasible and reproducible in daily clinical practice. Vestibular ELR values exceeding 60% defined radiologically significant vestibular hydrops, while values below 30% defined radiologically non-significant vestibular hydrops.