Domain organization of the OBPs found in the Ami system in S. pneumoniae [Dataset]

(A) Schematic representation illustrating the different elements composing the lipoproteins of the Ami system. Distinctive coloring is applied to each domain. (B) Alignment of sequences encompassing the signal peptide (in yellow), the lipobox (in red) and the linker region (in gray) in the five lipo...

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Detalhes bibliográficos
Autores: Alcorlo, Martín, Abdullah, Mohammed R., Steil, Leif, Sotomayor, Francisco, López de Oro, Laura, Castro, Sonia de, Velázquez, Sonsoles, Kohler, Thomas P., Jiménez, Elisabet, Medina, Ana, Usón, Isabel, Keller, Lance E., Bradshaw, Jessica L., McDaniel, Larry S., Camarasa Rius, María José, Völker, Uwe, Hammerschmidt, Sven, Hermoso, Juan A.
Formato: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/374362
Acesso em linha:http://hdl.handle.net/10261/374362
Access Level:acceso abierto
Palavra-chave:Unexpected remarkable promiscuity
Streptococcus pneumoniae </
Produced de novo
Multiple crystallographic structures
Escherichia coli </
Diverse peptide specificities
Closed conformations along
Certain amino acids
>, displaying affinity
Ensure sufficient uptake
Mass spectrometry analysis
div >< p
Orchestrating oligopeptide uptake
Four proteins building
Ami transporter system
Abc transporter channel
Pneumococci
Structural analysis
Oligopeptide recognition
Oligopeptide binding
Uptake mechanism
Wide range
Vivo implications
Transport systems
Substantial array
Structural basis
Silico modelling
Shedding light
Oligopeptides demonstrates
Invasive infections
Energy balance
Cellular cytoplasm
Cell surface
Binding cassette
Becomes indispensable
Auxotrophic nature
Abc transporters
Descrição
Resumo:(A) Schematic representation illustrating the different elements composing the lipoproteins of the Ami system. Distinctive coloring is applied to each domain. (B) Alignment of sequences encompassing the signal peptide (in yellow), the lipobox (in red) and the linker region (in gray) in the five lipoproteins of the Ami system. The cysteine residue designated for lipidation is denoted by a black arrow.

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