Challenges in diabetic macular edema management: An expert consensus report

Purpose: This paper aimed to present daily-practice recommendations for the management of diabetic macular edema (DME) patients based on available scientific evidence and the clinical experience of the consensus panel. Methods: A group of Spanish retina experts agreed to discuss different aspects re...

Descripción completa

Detalles Bibliográficos
Autores: Udaondo, Patricia, Adan, Alfredo, Arias-Barquet, Luis, Ascaso, Francisco J., Cabrera-López, Francisco, Castro-Navarro, Verónica, Donate-López, Juan, García-Layana, Alfredo, Lavid, Francisco Javier, Rodríguez-Maqueda, Mariano, Ruiz Moreno, José María
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/705099
Acceso en línea:http://hdl.handle.net/10486/705099
https://dx.doi.org/10.2147/OPTH.S320948
Access Level:acceso abierto
Palabra clave:Biomarkers
Consensus
Diabetes
Diabetic macular edema
Inflammation
Optical coherence tomography
Medicina
Descripción
Sumario:Purpose: This paper aimed to present daily-practice recommendations for the management of diabetic macular edema (DME) patients based on available scientific evidence and the clinical experience of the consensus panel. Methods: A group of Spanish retina experts agreed to discuss different aspects related with the clinical management of DME patients. Results: Panel was mainly focused on therapeutic objectives in DME management; definition terms; and role of biomarkers as prognostic and predictive factors to intravitreal treatment response. The panel recommends to start DME treatment as soon as possible in those eyes with a visual acuity less than 20/25 (always according to the retina unit capacity). Naïve patient was defined, in a strict manner, as a patient who, up to that moment, had never received any treatment. A refractory DME patient may be defined as the one who did not achieve a complete resolution of the disease, regardless of the treatment administered. Different optical coherence tomography biomarkers, such as disorganization of the retinal inner layers, hyperreflective dots, and cysts, have been identified as prognostic factors. Conclusion: This document has sought to lay down a set of recommendations and to identify key issues that may be useful for the daily management of DME patients.