Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico

The occurrence of aflatoxin M (AFM) in infant formulae commercialized in the metropolitan area of Monterrey (Nuevo León, Mexico) was determined by using immunoaffinity column clean-up followed by HPLC determination with fluorimetric detection. For this, 55 infant formula powders were classified in t...

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Autores: Quevedo-Garza, Patricia A., Amador-Espejo, Genaro G.|||0000-0002-9203-2530, Salas-García, Rogelio, Ramos-Peña, Esteban G., Trujillo, Antonio-José|||0000-0003-1437-6060
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:226249
Acceso en línea:https://ddd.uab.cat/record/226249
https://dx.doi.org/urn:doi:10.3390/toxins12020100
Access Level:acceso abierto
Palabra clave:AMF
Infant formulae
Estimated daily intake
Carcinogenic risk index
Monterrey (Mexico)
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spelling Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, MexicoQuevedo-Garza, Patricia A.Amador-Espejo, Genaro G.|||0000-0002-9203-2530Salas-García, RogelioRamos-Peña, Esteban G.Trujillo, Antonio-José|||0000-0003-1437-6060AMFInfant formulaeEstimated daily intakeCarcinogenic risk indexMonterrey (Mexico)The occurrence of aflatoxin M (AFM) in infant formulae commercialized in the metropolitan area of Monterrey (Nuevo León, Mexico) was determined by using immunoaffinity column clean-up followed by HPLC determination with fluorimetric detection. For this, 55 infant formula powders were classified in two groups, starter (49 samples) and follow-on (6 samples) formulae. Eleven of the evaluated samples (20%) presented values above the permissible limit set by the European Union for infant formulae (25 ng/L), ranging from 40 to 450 ng/L. The estimated daily intake (EDI) for AFM was determined employing the average body weight (bw) of the groups of age in the ranges of 0-6 and 6-12 months, and 1-2 years. The results evidenced high intake values, ranging from 1.56 to 14 ng/kg bw/day, depending on the group. Finally, with the EDI value, the carcinogenic risk index was determined, presenting a high risk for all the evaluated groups. Based on these results, it is a necessary extra effort by the regulatory agencies to reduce the AFM presence in infant formulae consumed in Mexico. 22020-01-0120202020-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/226249https://dx.doi.org/urn:doi:10.3390/toxins12020100reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2262492026-06-06T12:50:31Z
dc.title.none.fl_str_mv Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
title Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
spellingShingle Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
Quevedo-Garza, Patricia A.
AMF
Infant formulae
Estimated daily intake
Carcinogenic risk index
Monterrey (Mexico)
title_short Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
title_full Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
title_fullStr Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
title_full_unstemmed Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
title_sort Aflatoxin M Determination in Infant Formulae Distributed in Monterrey, Mexico
dc.creator.none.fl_str_mv Quevedo-Garza, Patricia A.
Amador-Espejo, Genaro G.|||0000-0002-9203-2530
Salas-García, Rogelio
Ramos-Peña, Esteban G.
Trujillo, Antonio-José|||0000-0003-1437-6060
author Quevedo-Garza, Patricia A.
author_facet Quevedo-Garza, Patricia A.
Amador-Espejo, Genaro G.|||0000-0002-9203-2530
Salas-García, Rogelio
Ramos-Peña, Esteban G.
Trujillo, Antonio-José|||0000-0003-1437-6060
author_role author
author2 Amador-Espejo, Genaro G.|||0000-0002-9203-2530
Salas-García, Rogelio
Ramos-Peña, Esteban G.
Trujillo, Antonio-José|||0000-0003-1437-6060
author2_role author
author
author
author
dc.subject.none.fl_str_mv AMF
Infant formulae
Estimated daily intake
Carcinogenic risk index
Monterrey (Mexico)
topic AMF
Infant formulae
Estimated daily intake
Carcinogenic risk index
Monterrey (Mexico)
description The occurrence of aflatoxin M (AFM) in infant formulae commercialized in the metropolitan area of Monterrey (Nuevo León, Mexico) was determined by using immunoaffinity column clean-up followed by HPLC determination with fluorimetric detection. For this, 55 infant formula powders were classified in two groups, starter (49 samples) and follow-on (6 samples) formulae. Eleven of the evaluated samples (20%) presented values above the permissible limit set by the European Union for infant formulae (25 ng/L), ranging from 40 to 450 ng/L. The estimated daily intake (EDI) for AFM was determined employing the average body weight (bw) of the groups of age in the ranges of 0-6 and 6-12 months, and 1-2 years. The results evidenced high intake values, ranging from 1.56 to 14 ng/kg bw/day, depending on the group. Finally, with the EDI value, the carcinogenic risk index was determined, presenting a high risk for all the evaluated groups. Based on these results, it is a necessary extra effort by the regulatory agencies to reduce the AFM presence in infant formulae consumed in Mexico.
publishDate 2020
dc.date.none.fl_str_mv 2
2020-01-01
2020
2020-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/226249
https://dx.doi.org/urn:doi:10.3390/toxins12020100
url https://ddd.uab.cat/record/226249
https://dx.doi.org/urn:doi:10.3390/toxins12020100
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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repository.mail.fl_str_mv
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