Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite

A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (65 nm) supported onto the HA particles (13...

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Detalhes bibliográficos
Autores: Díaz, Marcos, Barba, Flora, Miranda, Miriam, Guitián Rivera, Francisco, Torrecillas, Ramón, Moya, José S.
Tipo de documento: artigo
Data de publicação:2009
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositório:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglês
OAI Identifier:oai:minerva.usc.gal:10347/22568
Acesso em linha:http://hdl.handle.net/10347/22568
Access Level:Acceso aberto
Descrição
Resumo:A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (65 nm) supported onto the HA particles (130 nm) surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria has been also investigated. The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications.