SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)

Small-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately 15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical resection can be curative in early stages, followed by platinum-etoposide adjuvant therapy, although only a minority...

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Autores: García-Campelo, Rosario, Sullivan, Ivana, Arriola Aperribay, Edurne, Insa, Amelia, Juan Vidal, Óscar, Cruz-Castellanos, Patricia, Morán, Teresa, Reguart, Noemí, Zugazagoitia, Jon, Dómine, Manuel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/59965
Acceso en línea:http://hdl.handle.net/10230/59965
http://dx.doi.org/10.1007/s12094-023-03216-3
Access Level:acceso abierto
Palabra clave:Clinical practice guidelines
Diagnosis
Follow-up
Small-cell lung cancer
Treatment
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spelling SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)García-Campelo, RosarioSullivan, IvanaArriola Aperribay, EdurneInsa, AmeliaJuan Vidal, ÓscarCruz-Castellanos, PatriciaMorán, TeresaReguart, NoemíZugazagoitia, JonDómine, ManuelClinical practice guidelinesDiagnosisFollow-upSmall-cell lung cancerTreatmentSmall-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately 15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical resection can be curative in early stages, followed by platinum-etoposide adjuvant therapy, although only a minority of patients with SCLC qualify for surgery. Concurrent chemo-radiotherapy is the standard of care for LS-SCLC that is not surgically resectable, followed by prophylactic cranial irradiation (PCI) for patients without progression. For extensive-stage (ES)-SCLC, a combination of platinum and etoposide has historically been a mainstay of treatment. Recently, the efficacy of programmed death-ligand 1 inhibitors combined with chemotherapy has become the new front-line standard of care for ES-SCLC. Emerging knowledge regarding SCLC biology, including genomic characterization and molecular subtyping, and new treatment approaches will potentially lead to advances in SCLC patient care.Springer202420242023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/59965http://dx.doi.org/10.1007/s12094-023-03216-3reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésClin Transl Oncol. 2023 Sep;25(9):2679-91© The Author(s) 2023, corrected publication 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/599652026-05-29T05:05:01Z
dc.title.none.fl_str_mv SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
title SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
spellingShingle SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
García-Campelo, Rosario
Clinical practice guidelines
Diagnosis
Follow-up
Small-cell lung cancer
Treatment
title_short SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
title_full SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
title_fullStr SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
title_full_unstemmed SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
title_sort SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)
dc.creator.none.fl_str_mv García-Campelo, Rosario
Sullivan, Ivana
Arriola Aperribay, Edurne
Insa, Amelia
Juan Vidal, Óscar
Cruz-Castellanos, Patricia
Morán, Teresa
Reguart, Noemí
Zugazagoitia, Jon
Dómine, Manuel
author García-Campelo, Rosario
author_facet García-Campelo, Rosario
Sullivan, Ivana
Arriola Aperribay, Edurne
Insa, Amelia
Juan Vidal, Óscar
Cruz-Castellanos, Patricia
Morán, Teresa
Reguart, Noemí
Zugazagoitia, Jon
Dómine, Manuel
author_role author
author2 Sullivan, Ivana
Arriola Aperribay, Edurne
Insa, Amelia
Juan Vidal, Óscar
Cruz-Castellanos, Patricia
Morán, Teresa
Reguart, Noemí
Zugazagoitia, Jon
Dómine, Manuel
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Clinical practice guidelines
Diagnosis
Follow-up
Small-cell lung cancer
Treatment
topic Clinical practice guidelines
Diagnosis
Follow-up
Small-cell lung cancer
Treatment
description Small-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately 15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical resection can be curative in early stages, followed by platinum-etoposide adjuvant therapy, although only a minority of patients with SCLC qualify for surgery. Concurrent chemo-radiotherapy is the standard of care for LS-SCLC that is not surgically resectable, followed by prophylactic cranial irradiation (PCI) for patients without progression. For extensive-stage (ES)-SCLC, a combination of platinum and etoposide has historically been a mainstay of treatment. Recently, the efficacy of programmed death-ligand 1 inhibitors combined with chemotherapy has become the new front-line standard of care for ES-SCLC. Emerging knowledge regarding SCLC biology, including genomic characterization and molecular subtyping, and new treatment approaches will potentially lead to advances in SCLC patient care.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/59965
http://dx.doi.org/10.1007/s12094-023-03216-3
url http://hdl.handle.net/10230/59965
http://dx.doi.org/10.1007/s12094-023-03216-3
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Clin Transl Oncol. 2023 Sep;25(9):2679-91
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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