Aerobic Visible-Light-Driven Borylation of Heteroarenes in a Gel Nanoreactor

[EN] Heteroarene boronate esters constitute valuable intermediates in modern organic synthesis. As building blocks, they can be further applied to the synthesis of new materials, since they can be easily transformed into any other functional group. Efforts toward novel and efficient strategies for t...

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Detalhes bibliográficos
Autores: Herrera-Luna, Jorge Carlos|||0000-0003-2992-7339, Encinas Perea, Susana|||0000-0001-5275-8436, Jiménez, M Consuelo|||0000-0002-8057-4316, Pérez-Ruiz, Raúl|||0000-0003-1136-3598, Díaz Díaz, David, Abramov, Alex
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/189905
Acesso em linha:https://riunet.upv.es/handle/10251/189905
Access Level:acceso abierto
Palavra-chave:Aerobic gel
Nanoreactor
Visible light
Borylation
Heteroarenes
QUIMICA ORGANICA
Descrição
Resumo:[EN] Heteroarene boronate esters constitute valuable intermediates in modern organic synthesis. As building blocks, they can be further applied to the synthesis of new materials, since they can be easily transformed into any other functional group. Efforts toward novel and efficient strategies for their preparation are clearly desirable. Here, we have achieved the borylation of commercially available heteroarene halides under very mild conditions in an easy-to-use gel nanoreactor. Its use of visible light as the energy source at room temperature in photocatalyst-free and aerobic conditions makes this protocol very attractive. The gel network provides an adequate stabilizing microenvironment to support wide substrate scope, including furan, thiophene, selenophene, and pyrrole boronate esters.