The Potential Application of AZ31-Mg(OH)2/CeO2 as Temporary Medical Implants: Evaluation of the Corrosion Resistance and Biocompatibility Properties
Magnesium-based alloys are considered to be promising materials for the fabrication of temporary bone repair medical implants. The AZ31 magnesium-based (AZ31-Mg) alloy contains 3% aluminum and 1% zinc in its microstructure, which gives it mechanical strength and corrosion resistance. Nonetheless, th...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/390534 |
| Acceso en línea: | http://hdl.handle.net/10261/390534 |
| Access Level: | acceso abierto |
| Palabra clave: | AZ31-Mg Biomaterial CeO2 coating Corrosion rate Biocompatibility |
| Sumario: | Magnesium-based alloys are considered to be promising materials for the fabrication of temporary bone repair medical implants. The AZ31 magnesium-based (AZ31-Mg) alloy contains 3% aluminum and 1% zinc in its microstructure, which gives it mechanical strength and corrosion resistance. Nonetheless, the corrosion rate is high, which can lead to implant failure due to rapid degradation, which triggers the release of harmful metal ions. In the present work, a passive layer was obtained on the AZ31-Mg alloy, and subsequently, a cerium oxide (CeO2) coating was deposited through a chemical conversion treatment using 0.01 M CeO2 as a precursor. Based on X-ray photoelectron spectroscopy, the calculated amount of Ce(IV) and Ce(III) present in AZ31-Mg(OH)2/CeO2 was 93.6% and 6.4%, respectively. AZ31-Mg(OH)2/CeO2 showed improved corrosion resistance compared with the bare sample. The in vitro assessment of MC3T3-E1 pre-osteoblast cell viability showed that AZ31-Mg(OH)2/CeO2 was biocompatible after incubation for 24 and 72 h. The results revealed that the CeO2 coating confers greater electrochemical stability and biocompatibility properties, mostly due to the presence of Ce4+ ions. |
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