Hemorrhagic stroke lesion segmentation using a 3D U-Net with squeeze-and-excitation blocks

Hemorrhagic stroke is the condition involving the rupture of a vessel inside the brain and is characterized by high mortality rates. Even if the patient survives, stroke can cause temporary or permanent disability depending on how long blood flow has been interrupted. Therefore, it is crucial to act...

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Detalles Bibliográficos
Autores: Abramova, Valeriia, Clèrigues Garcia, Albert, Quiles, Ana, Garcia Figueredo, Deysi, Silva Blas, Yolanda, Pedraza, S., Oliver i Malagelada, Arnau, Lladó Bardera, Xavier
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/20462
Acceso en línea:http://hdl.handle.net/10256/20462
Access Level:acceso abierto
Palabra clave:Imatgeria per ressonància magnètica
Magnetic resonance imaging
Isquèmia cerebral -- Imatgeria per ressonància magnètica
Cerebral ischemia -- Magnetic resonance imaging
Imatgeria per al diagnòstic
Diagnostic imaging
Descripción
Sumario:Hemorrhagic stroke is the condition involving the rupture of a vessel inside the brain and is characterized by high mortality rates. Even if the patient survives, stroke can cause temporary or permanent disability depending on how long blood flow has been interrupted. Therefore, it is crucial to act fast to prevent irreversible damage. In this work, a deep learning-based approach to automatically segment hemorrhagic stroke lesions in CT scans is proposed. Our approach is based on a 3D U-Net architecture which incorporates the recently proposed squeeze-and-excitation blocks. Moreover, a restrictive patch sampling is proposed to alleviate the class imbalance problem and also to deal with the issue of intra-ventricular hemorrhage, which has not been considered as a stroke lesion in our study. Moreover, we also analyzed the effect of patch size, the use of different modalities, data augmentation and the incorporation of different loss functions on the segmentation results. All analyses have been performed using a five fold cross-validation strategy on a clinical dataset composed of 76 cases. Obtained results demonstrate that the introduction of squeeze-and-excitation blocks, together with the restrictive patch sampling and symmetric modality augmentation, significantly improved the obtained results, achieving a mean DSC of 086 +- 0.074, showing promising automated segmentation results