Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates

Ethylcellulose nano-emulsions have been obtained by the low-energy phase inversion composition method in the Water / [Alkylamidoammonium: Cremophor WO7] / [6% ethylcellulose in ethyl acetate] system at 25 °C. It is shown that nano-emlulsions' composition variables (oil-to-surfactant ratio, cati...

Descripción completa

Detalles Bibliográficos
Autores: Calderó Linnhoff, Gabriela, Leitner, Stefanie, García Celma, Ma José, Solans Marsà, Conxita
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/178927
Acceso en línea:https://hdl.handle.net/2445/178927
Access Level:acceso abierto
Palabra clave:Nanopartícules
Emulsions (Farmàcia)
Nanofluids
Materials nanoestructurats
Nanoparticles
Emulsions (Pharmacy)
Nanostructured materials
id ES_a4b90b54d0c8136f0bdfebafd525b3ad
oai_identifier_str oai:recercat.cat:2445/178927
network_acronym_str ES
network_name_str España
repository_id_str
spelling Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templatesCalderó Linnhoff, GabrielaLeitner, StefanieGarcía Celma, Ma JoséSolans Marsà, ConxitaNanopartículesEmulsions (Farmàcia)NanofluidsMaterials nanoestructuratsNanoparticlesEmulsions (Pharmacy)NanofluidsNanostructured materialsEthylcellulose nano-emulsions have been obtained by the low-energy phase inversion composition method in the Water / [Alkylamidoammonium: Cremophor WO7] / [6% ethylcellulose in ethyl acetate] system at 25 °C. It is shown that nano-emlulsions' composition variables (oil-to-surfactant ratio, cationic: nonionic surfactant ratio and polymer and water content) produce changes in their droplet diameter, surface charge and colloidal stability following defined trends. Nano-emulsions with good stability, droplet diameters between about 120 and 200 nm and surface charge from about 10 to 50 mV have been obtained. Nano-emulsions are further used as templates for nanoparticle dispersions preparation, which show sizes and surface charges typically smaller and similar respectively to their nano-emulsion templates. Cationic: nonionic surfactant ratio has the highest influence on both, size and surface charge, followed by oil-to-surfactant ratio and water content. Interestingly, the positive charge of the nanoparticles can be depleted under diluting conditions in a time-dependent manner.Elsevier B.V.2021202120192021info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2445/178927Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1016/j.carbpol.2019.115201Carbohydrate Polymers, 2019, vol. 225https://doi.org/10.1016/j.carbpol.2019.115201cc-by-nc-nd (c) Elsevier B.V., 2019https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1789272026-05-29T05:05:01Z
dc.title.none.fl_str_mv Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
title Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
spellingShingle Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
Calderó Linnhoff, Gabriela
Nanopartícules
Emulsions (Farmàcia)
Nanofluids
Materials nanoestructurats
Nanoparticles
Emulsions (Pharmacy)
Nanofluids
Nanostructured materials
title_short Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
title_full Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
title_fullStr Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
title_full_unstemmed Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
title_sort Modulating size and surface charge of ethylcellulose nanoparticles through the use of cationic nano-emulsion templates
dc.creator.none.fl_str_mv Calderó Linnhoff, Gabriela
Leitner, Stefanie
García Celma, Ma José
Solans Marsà, Conxita
author Calderó Linnhoff, Gabriela
author_facet Calderó Linnhoff, Gabriela
Leitner, Stefanie
García Celma, Ma José
Solans Marsà, Conxita
author_role author
author2 Leitner, Stefanie
García Celma, Ma José
Solans Marsà, Conxita
author2_role author
author
author
dc.subject.none.fl_str_mv Nanopartícules
Emulsions (Farmàcia)
Nanofluids
Materials nanoestructurats
Nanoparticles
Emulsions (Pharmacy)
Nanofluids
Nanostructured materials
topic Nanopartícules
Emulsions (Farmàcia)
Nanofluids
Materials nanoestructurats
Nanoparticles
Emulsions (Pharmacy)
Nanofluids
Nanostructured materials
description Ethylcellulose nano-emulsions have been obtained by the low-energy phase inversion composition method in the Water / [Alkylamidoammonium: Cremophor WO7] / [6% ethylcellulose in ethyl acetate] system at 25 °C. It is shown that nano-emlulsions' composition variables (oil-to-surfactant ratio, cationic: nonionic surfactant ratio and polymer and water content) produce changes in their droplet diameter, surface charge and colloidal stability following defined trends. Nano-emulsions with good stability, droplet diameters between about 120 and 200 nm and surface charge from about 10 to 50 mV have been obtained. Nano-emulsions are further used as templates for nanoparticle dispersions preparation, which show sizes and surface charges typically smaller and similar respectively to their nano-emulsion templates. Cationic: nonionic surfactant ratio has the highest influence on both, size and surface charge, followed by oil-to-surfactant ratio and water content. Interestingly, the positive charge of the nanoparticles can be depleted under diluting conditions in a time-dependent manner.
publishDate 2019
dc.date.none.fl_str_mv 2019
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/178927
url https://hdl.handle.net/2445/178927
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1016/j.carbpol.2019.115201
Carbohydrate Polymers, 2019, vol. 225
https://doi.org/10.1016/j.carbpol.2019.115201
dc.rights.none.fl_str_mv cc-by-nc-nd (c) Elsevier B.V., 2019
https://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc-nd (c) Elsevier B.V., 2019
https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869415538752487424
score 15.812429

Similares en LA Referencia