Preblastoderm mosaics of mutants of the bithorax-complex

InDrosophila melanogaster, segmental specification takes place in groups of cells around the blastoderm stage. This segmental specification requires the function of the genes of the bithorax-complex. We have studied preblastoderm mosaics (gynandromorphs) of mutant (bx 3,pbx, Ubx, Ubx 80) and wildtyp...

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Bibliographic Details
Authors: Miñana, F. J., García-Bellido, Antonio
Format: article
Publication Date:1982
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/47693
Online Access:http://hdl.handle.net/10261/47693
Access Level:Embargoed access
Keyword:Genetic mosaics
Cell autonomy
Cell affinities
Drosophila melanogaster
Description
Summary:InDrosophila melanogaster, segmental specification takes place in groups of cells around the blastoderm stage. This segmental specification requires the function of the genes of the bithorax-complex. We have studied preblastoderm mosaics (gynandromorphs) of mutant (bx 3,pbx, Ubx, Ubx 80) and wildtype (heterozygotes for these alleles) cells. The results show a total cell autonomy in the differentiation of both wildtype and homoeotially transformed cells. However, several unexpected phenotypes were found. They are discussed in terms of the function of the bithorax genes and early interactions between mutant and wildtype territories.