Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys

Aims: Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and...

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Authors: Roest, Annelieke M., Alonso Caballero, Jordi, WHO World Mental Health Survey Collaborators
Format: article
Status:Published version
Publication Date:2021
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/49156
Online Access:http://hdl.handle.net/10230/49156
http://dx.doi.org/10.1017/S2045796021000573
Access Level:Open access
Keyword:Comorbidity
Impairment
Major depressive disorder
Suicidal thoughts and behaviours
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spelling Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveysRoest, Annelieke M.Alonso Caballero, JordiWHO World Mental Health Survey CollaboratorsComorbidityImpairmentMajor depressive disorderSuicidal thoughts and behavioursAims: Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and the impact of these disorders on depression outcomes. Methods: Data came from 29 cross-sectional community epidemiological surveys of adults in 27 countries (n = 80 190). The Composite International Diagnostic Interview (CIDI) was used to assess 12-month MDD and lifetime DSM-IV disorders with onset prior to the respondent's age at interview. Disorders were grouped into depressive distress disorders, non-depressive distress disorders, fear disorders and externalising disorders. Depression outcomes included 12-month suicidality, days out of role and impairment in role functioning. Results: Among respondents with 12-month MDD, 94.9% (s.e. = 0.4) had at least one prior disorder (including previous MDD), and 64.6% (s.e. = 0.9) had at least one prior, non-MDD disorder. Previous non-depressive distress, fear and externalising disorders, but not depressive distress disorders, predicted higher impairment (OR = 1.4-1.6) and suicidality (OR = 1.5-2.5), after adjustment for sociodemographic variables. Further adjustment for MDD characteristics weakened, but did not eliminate, these associations. Associations were largely driven by current comorbidities, but both remitted and current externalising disorders predicted suicidality among respondents with 12-month MDD. Conclusions: These results illustrate the importance of careful psychiatric history taking regarding current anxiety disorders and lifetime externalising disorders in individuals with MDD.Cambridge University Press202120212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/49156http://dx.doi.org/10.1017/S2045796021000573reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésEpidemiol Psychiatr Sci. 2021;30:e70© The Author(s), 2021. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/491562026-06-12T07:21:37Z
dc.title.none.fl_str_mv Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
title Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
spellingShingle Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
Roest, Annelieke M.
Comorbidity
Impairment
Major depressive disorder
Suicidal thoughts and behaviours
title_short Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
title_full Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
title_fullStr Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
title_full_unstemmed Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
title_sort Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys
dc.creator.none.fl_str_mv Roest, Annelieke M.
Alonso Caballero, Jordi
WHO World Mental Health Survey Collaborators
author Roest, Annelieke M.
author_facet Roest, Annelieke M.
Alonso Caballero, Jordi
WHO World Mental Health Survey Collaborators
author_role author
author2 Alonso Caballero, Jordi
WHO World Mental Health Survey Collaborators
author2_role author
author
dc.subject.none.fl_str_mv Comorbidity
Impairment
Major depressive disorder
Suicidal thoughts and behaviours
topic Comorbidity
Impairment
Major depressive disorder
Suicidal thoughts and behaviours
description Aims: Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and the impact of these disorders on depression outcomes. Methods: Data came from 29 cross-sectional community epidemiological surveys of adults in 27 countries (n = 80 190). The Composite International Diagnostic Interview (CIDI) was used to assess 12-month MDD and lifetime DSM-IV disorders with onset prior to the respondent's age at interview. Disorders were grouped into depressive distress disorders, non-depressive distress disorders, fear disorders and externalising disorders. Depression outcomes included 12-month suicidality, days out of role and impairment in role functioning. Results: Among respondents with 12-month MDD, 94.9% (s.e. = 0.4) had at least one prior disorder (including previous MDD), and 64.6% (s.e. = 0.9) had at least one prior, non-MDD disorder. Previous non-depressive distress, fear and externalising disorders, but not depressive distress disorders, predicted higher impairment (OR = 1.4-1.6) and suicidality (OR = 1.5-2.5), after adjustment for sociodemographic variables. Further adjustment for MDD characteristics weakened, but did not eliminate, these associations. Associations were largely driven by current comorbidities, but both remitted and current externalising disorders predicted suicidality among respondents with 12-month MDD. Conclusions: These results illustrate the importance of careful psychiatric history taking regarding current anxiety disorders and lifetime externalising disorders in individuals with MDD.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/49156
http://dx.doi.org/10.1017/S2045796021000573
url http://hdl.handle.net/10230/49156
http://dx.doi.org/10.1017/S2045796021000573
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Epidemiol Psychiatr Sci. 2021;30:e70
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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