Hepatitis A virus in urban sewage from two Mediterranean countries.

Molecular methods for the detection and typing of hepatitis A virus (HAV) strains in sewage were applied to determine its distribution in Cairo and Barcelona. The study revealed the occurrence of different patterns of hepatitis A endemicity in each city. The circulating strains characterized, whethe...

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Detalles Bibliográficos
Autores: Pintó Solé, Rosa María, Alegre, D., Domínguez García, Àngela, Morsy El-Senousy, W., Sánchez, G., Villena, C., Costafreda Salvany, M. Isabel (Maria Isabel), Aragonès, L., Bosch, Albert
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/193905
Acceso en línea:https://hdl.handle.net/2445/193905
Access Level:acceso abierto
Palabra clave:Hepatitis A
Virus de l'hepatitis A
Hepatitis A virus
Descripción
Sumario:Molecular methods for the detection and typing of hepatitis A virus (HAV) strains in sewage were applied to determine its distribution in Cairo and Barcelona. The study revealed the occurrence of different patterns of hepatitis A endemicity in each city. The circulating strains characterized, whether in Cairo or Barcelona, were genotype IB. The effects of a child vaccination programme and the increase in the immigrant population on the overall hepatitis A occurrence in Barcelona were evaluated. While vaccination contributed to a significant decrease in the number of clinical cases, the huge recent immigration flow has probably been responsible for the re-emergence of the disease in the last year of study, in the form of small outbreaks among the non-vaccinated population.