Free-form image registration of human cochlear μ CT data using skeleton similarity as anatomical prior

Better understanding of the anatomical variability of the human cochlear is important for the design and function of Cochlear Implants. Proper non-rigid alignment of high-resolution cochlear μCT data is a challenge for the typical cubic B-spline registration model. In this paper we study one way of...

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Detalles Bibliográficos
Autores: Kjer, Hans Martin, Fagertun, Jens, Vera, Sergio, Gil, Debora, González Ballester, Miguel Ángel, 1973-, Paulsen, Rasmus R.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/59141
Acceso en línea:http://hdl.handle.net/10230/59141
http://dx.doi.org/10.1016/j.patrec.2015.07.017
Access Level:acceso abierto
Palabra clave:Image registration
Regularization
Skeleton
Cochlea
Inner ear
Descripción
Sumario:Better understanding of the anatomical variability of the human cochlear is important for the design and function of Cochlear Implants. Proper non-rigid alignment of high-resolution cochlear μCT data is a challenge for the typical cubic B-spline registration model. In this paper we study one way of incorporating skeleton-based similarity as an anatomical registration prior. We extract a centerline skeleton of the cochlear spiral, and generate corresponding parametric pseudo-landmarks between samples. These correspondences are included in the cost function of a typical cubic B-spline registration model to provide a more global guidance of the alignment. The resulting registrations are evaluated using different metrics for accuracy and model behavior, and compared to