Bidirectional holograms for transcranial therapeutic ultrasound

[EN] Acoustic holograms are emerging as a new therapeutic approach to focus ultrasound energy into human tissues. Holograms are suited to generate sharp acoustic images and, in addition, the phase aberrations produced by tissues such as skull bones can be compensated. However, these lenses present a...

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Detalles Bibliográficos
Autor: Valle Sánchez, Marta
Tipo de recurso: tesis de maestría
Fecha de publicación:2025
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/228335
Acceso en línea:https://riunet.upv.es/handle/10251/228335
Access Level:acceso abierto
Palabra clave:Hologramas acústicos
Terápias transcraneles con ultrasonido
Lentes anatómicas.
Acoustic holograms
Transcranial therapeutic ultrasound
Matching layers.
Máster Universitario en Ingeniería Acústica-Màster Universitari en Enginyeria Acústica
Descripción
Sumario:[EN] Acoustic holograms are emerging as a new therapeutic approach to focus ultrasound energy into human tissues. Holograms are suited to generate sharp acoustic images and, in addition, the phase aberrations produced by tissues such as skull bones can be compensated. However, these lenses present a rough and irregular shape that make difficult its coupling with the human skin. In this work, we exploit the reciprocity of the mechanical waves to manufacture lenses that present either a flatter surface in the radiating face. This face can be designed to fit over the skin, easily adapting to different anatomical areas of the head, such as the temporal bone window, enhancing the coupling of the lens to the patient head. To validate this approach a set of acoustic simulations considering different materials to design the holographic lens are considered. In this way, this approach results in a compact wearable device for transcranial therapeutic ultrasound applications such as neuromodulation, localized drug delivery or focused hyperthermia.