High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food

[EN] As in the case of the food industry in general, there is a global concern about safety and quality in complex food matrices, such as honey, which is driving the demand for fast, sensitive and affordable analytical techniques across the honey-packaging industry. Although excellent techniques suc...

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Autores: Calero-Alcarria, María Del Señor, García, María, Montoya, Ángel, FERNÁNDEZ DÍAZ, ROMÁN|||0000-0002-8883-4653, Juan-Borras, María del Sol|||0000-0003-4774-9484, Escriche Roberto, Mª Isabel|||0000-0003-0180-0360, Arnau Vives, Antonio|||0000-0002-5709-1690, Jiménez Jiménez, Yolanda|||0000-0003-4835-9007
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/195330
Acceso en línea:https://riunet.upv.es/handle/10251/195330
Access Level:acceso abierto
Palabra clave:Immunosensor
HFF-QCMD array
Honey
Antibiotic
Pesticide
TECNOLOGIA DE ALIMENTOS
TECNOLOGIA ELECTRONICA
02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible
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network_name_str España
repository_id_str
dc.title.none.fl_str_mv High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
title High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
spellingShingle High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
Calero-Alcarria, María Del Señor
Immunosensor
HFF-QCMD array
Honey
Antibiotic
Pesticide
TECNOLOGIA DE ALIMENTOS
TECNOLOGIA ELECTRONICA
02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible
title_short High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
title_full High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
title_fullStr High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
title_full_unstemmed High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
title_sort High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex Food
dc.creator.none.fl_str_mv Calero-Alcarria, María Del Señor
García, María
Montoya, Ángel
FERNÁNDEZ DÍAZ, ROMÁN|||0000-0002-8883-4653
Juan-Borras, María del Sol|||0000-0003-4774-9484
Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Arnau Vives, Antonio|||0000-0002-5709-1690
Jiménez Jiménez, Yolanda|||0000-0003-4835-9007
author Calero-Alcarria, María Del Señor
author_facet Calero-Alcarria, María Del Señor
García, María
Montoya, Ángel
FERNÁNDEZ DÍAZ, ROMÁN|||0000-0002-8883-4653
Juan-Borras, María del Sol|||0000-0003-4774-9484
Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Arnau Vives, Antonio|||0000-0002-5709-1690
Jiménez Jiménez, Yolanda|||0000-0003-4835-9007
author_role author
author2 García, María
Montoya, Ángel
FERNÁNDEZ DÍAZ, ROMÁN|||0000-0002-8883-4653
Juan-Borras, María del Sol|||0000-0003-4774-9484
Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Arnau Vives, Antonio|||0000-0002-5709-1690
Jiménez Jiménez, Yolanda|||0000-0003-4835-9007
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Tecnología de Alimentos
Departamento de Ingeniería Electrónica
Escuela Técnica Superior de Ingeniería de Telecomunicación
Escuela Técnica Superior de Ingeniería Aeroespacial y Diseño Industrial
Instituto Universitario de Ingeniería de Alimentos (FoodUPV)
Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural
Centro de Investigación e Innovación en Bioingeniería
AGENCIA ESTATAL DE INVESTIGACION
Ministerio de Economía y Empresa
Agencia Estatal de Investigación
European Regional Development Fund
Ministerio de Economía, Industria y Competitividad
Universitat Politècnica de València
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Immunosensor
HFF-QCMD array
Honey
Antibiotic
Pesticide
TECNOLOGIA DE ALIMENTOS
TECNOLOGIA ELECTRONICA
02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible
topic Immunosensor
HFF-QCMD array
Honey
Antibiotic
Pesticide
TECNOLOGIA DE ALIMENTOS
TECNOLOGIA ELECTRONICA
02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible
description [EN] As in the case of the food industry in general, there is a global concern about safety and quality in complex food matrices, such as honey, which is driving the demand for fast, sensitive and affordable analytical techniques across the honey-packaging industry. Although excellent techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) are available, these are located in centralized laboratories and are still lacking in speed, simplicity and cost-effectiveness. Here, a new approach is presented where a competitive immunoassay is combined with a novel High Fundamental Frequency Quartz Crystal Microbalance with Dissipation (HFF-QCMD) array biosensor for the simultaneous detection of antibiotics and pesticides in honey. Concretely, thiabendazole and sulfathiazole residues were monitored in spiked honey samples. Results revealed that HFF-QCMD arrays provide a complementary and reliable tool to LC-MS/MS for the analysis of contaminants in these kinds of complex matrices, while avoiding elaborate sample pre-treatment. The good sensitivity achieved (I50 values in the 70¿720 µg/kg range) and the short analysis time (60 min for 24 individual assays), together with the ability for multiple analyte detection (24 sensor array) and its cost-effectiveness, pave the way for the implementation of a fast on-line, in situ routine control of potentially hazardous chemical residues in honey.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-06-20
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/195330
url https://riunet.upv.es/handle/10251/195330
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 AGL2013-48646-R DISEÑO DE UNA PLATAFORMA BASADA EN MATRICES DE SENSORES DE CUARZO DE ALTA RESOLUCION PARA HTS (HIGH-THROUGHPUT SCREENING) DE RESIDUOS EN MIELES
Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 AGL2016-77702-R DISEÑO DE UN BIOSENSOR DE ADN BASADO EN TECNOLOGIA HFF-QCM PARA LA DETECCION DE SUSTANCIAS ADULTERANTES EN MIEL
Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 BES-2017-080246 DISEÑO DE UN BIOSENSOR DE ADN BASADO EN TECNOLOGIA HFF-QCM PARA LA DETECCION DE SUSTANCIAS ADULTERANTES EN MIEL
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI AG
publisher.none.fl_str_mv MDPI AG
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling High Fundamental Frequency (HFF) Monolithic Quartz Crystal Microbalance with Dissipation Array for the Simultaneous Detection of Pesticides and Antibiotics in Complex FoodCalero-Alcarria, María Del SeñorGarcía, MaríaMontoya, ÁngelFERNÁNDEZ DÍAZ, ROMÁN|||0000-0002-8883-4653Juan-Borras, María del Sol|||0000-0003-4774-9484Escriche Roberto, Mª Isabel|||0000-0003-0180-0360Arnau Vives, Antonio|||0000-0002-5709-1690Jiménez Jiménez, Yolanda|||0000-0003-4835-9007ImmunosensorHFF-QCMD arrayHoneyAntibioticPesticideTECNOLOGIA DE ALIMENTOSTECNOLOGIA ELECTRONICA02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible[EN] As in the case of the food industry in general, there is a global concern about safety and quality in complex food matrices, such as honey, which is driving the demand for fast, sensitive and affordable analytical techniques across the honey-packaging industry. Although excellent techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) are available, these are located in centralized laboratories and are still lacking in speed, simplicity and cost-effectiveness. Here, a new approach is presented where a competitive immunoassay is combined with a novel High Fundamental Frequency Quartz Crystal Microbalance with Dissipation (HFF-QCMD) array biosensor for the simultaneous detection of antibiotics and pesticides in honey. Concretely, thiabendazole and sulfathiazole residues were monitored in spiked honey samples. Results revealed that HFF-QCMD arrays provide a complementary and reliable tool to LC-MS/MS for the analysis of contaminants in these kinds of complex matrices, while avoiding elaborate sample pre-treatment. The good sensitivity achieved (I50 values in the 70¿720 µg/kg range) and the short analysis time (60 min for 24 individual assays), together with the ability for multiple analyte detection (24 sensor array) and its cost-effectiveness, pave the way for the implementation of a fast on-line, in situ routine control of potentially hazardous chemical residues in honey.This work was supported by Ministerio de Economía, Industria y Competitividad de España-Agencia Estatal de Investigación with FEDER (Fondo Europeo de Desarrollo Regional) funds under Grants AGL2016-77702-R and AGL2013-48646-R. M. Calero is the recipient of the doctoral fellowship BES-2017-080246 from the Ministerio de Economía, Industria y Competitividad de España.MDPI AGDepartamento de Tecnología de AlimentosDepartamento de Ingeniería ElectrónicaEscuela Técnica Superior de Ingeniería de TelecomunicaciónEscuela Técnica Superior de Ingeniería Aeroespacial y Diseño IndustrialInstituto Universitario de Ingeniería de Alimentos (FoodUPV)Escuela Técnica Superior de Ingeniería Agronómica y del Medio NaturalCentro de Investigación e Innovación en BioingenieríaAGENCIA ESTATAL DE INVESTIGACIONMinisterio de Economía y EmpresaAgencia Estatal de InvestigaciónEuropean Regional Development FundMinisterio de Economía, Industria y CompetitividadUniversitat Politècnica de ValènciaRepositorio Institucional de la Universitat Politècnica de València Riunet20222022-06-20journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/195330reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 AGL2013-48646-R DISEÑO DE UNA PLATAFORMA BASADA EN MATRICES DE SENSORES DE CUARZO DE ALTA RESOLUCION PARA HTS (HIGH-THROUGHPUT SCREENING) DE RESIDUOS EN MIELESAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 AGL2016-77702-R DISEÑO DE UN BIOSENSOR DE ADN BASADO EN TECNOLOGIA HFF-QCM PARA LA DETECCION DE SUSTANCIAS ADULTERANTES EN MIELAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 BES-2017-080246 DISEÑO DE UN BIOSENSOR DE ADN BASADO EN TECNOLOGIA HFF-QCM PARA LA DETECCION DE SUSTANCIAS ADULTERANTES EN MIELopen accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento (by)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/1953302026-06-13T07:49:27Z
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