Chimpanzee genomic diversity reveals ancient admixture with bonobos

Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of g...

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Detalles Bibliográficos
Autores: de Manuel, Marc, Kuhlwilm, Martin, Sousa, Victor C., Prado Martínez, Javier, 1987-, Hernández Rodríguez, Jéssica, 1983-, Dupanloup, Isabelle, Lao Grueso, Oscar, 1976-, Heredia Genestar, José María, 1985-, Kuderna, Lukas, 1989-, Casals López, Ferran, Angedakin, Samuel, Arandjelovic, Mimi, Boesch, Christophe, Kühl, Hjalmar S., Vigilant, Linda, Navarro i Cuartiellas, Arcadi, 1969-, Excoffier, Laurent, Marquès i Bonet, Tomàs, 1975-
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2016
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/35987
Acceso en línea:http://hdl.handle.net/10230/35987
http://dx.doi.org/10.1126/science.aag2602
Access Level:acceso abierto
Palabra clave:Evolució molecular
Genètica
Bonobo -- Genètica
Ximpanzés -- Genètica
Descripción
Sumario:Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 years ago, probably with subsequent spread into Nigeria-Cameroon chimpanzees. Together with another, possibly more recent contact (after 200,000 years ago), bonobos contributed less than 1% to the central chimpanzee genomes. Admixture thus appears to have been widespread during hominid evolution.