Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments

[Objective] Blood-biomarkers have the potential to aid clinicians in pediatric emergency departments (PED) in managing children with mild traumatic brain injury (mTBI) acutely. However, studies focusing on pediatric populations remain limited. We aim to assess the performances of two routinely used...

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Detalles Bibliográficos
Autores: Chiollaz, Anne-Cécile, Pouillard, Virginie, Seiler, Michelle, Habre, Céline, Romano, Fabrizio, Ritter Schenck, Céline, Spigariol, Fabian, Korff, Christian, Maréchal, Fabienne, Wyss, Verena, Gruaz, Lyssia, Montaner, Joan, Sanchez, Jean-Charles, Manzano, Sergio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/390826
Acceso en línea:http://hdl.handle.net/10261/390826
https://api.elsevier.com/content/abstract/scopus_id/85218047648
Access Level:acceso abierto
Palabra clave:Blood-biomarkers
Diagnosis
Emergency
mTBI
Pediatric
Descripción
Sumario:[Objective] Blood-biomarkers have the potential to aid clinicians in pediatric emergency departments (PED) in managing children with mild traumatic brain injury (mTBI) acutely. However, studies focusing on pediatric populations remain limited. We aim to assess the performances of two routinely used biomarkers in other fields: the neurofilament light chain protein (NfL), and the N-terminal prohormone of brain natriuretic peptide (NTproBNP), to safely discharge children without intracranial injuries (ICIs).

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