Response to therapeutic abortion in lactating dairy cows carrying dead twins during the late embryo/early fetal period

This study examined the dose–response effect of prostaglandin F2α (PGF2α) when used to induce abortion in cows with two dead twins at pregnancy diagnosis 28–34 days post-AI (late embryonic period: LE) or at pregnancy confirmation 49–55 days post-AI (early fetal period: EF). The study population cons...

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Detalles Bibliográficos
Autor: López Gatius, Fernando
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/72925
Acceso en línea:https://doi.org/10.3390/ani11092508
http://hdl.handle.net/10459.1/72925
Access Level:acceso abierto
Palabra clave:Dead conceptuses
Delayed luteolysis
Necroidentificació
Avortament
Fetus--Mort
Embaràs múltiple
Vaques
Bestiar boví
Descripción
Sumario:This study examined the dose–response effect of prostaglandin F2α (PGF2α) when used to induce abortion in cows with two dead twins at pregnancy diagnosis 28–34 days post-AI (late embryonic period: LE) or at pregnancy confirmation 49–55 days post-AI (early fetal period: EF). The study population consisted of 415 cows receiving a single PGF2α dose (PG1 group: 254 LE and 161 EF cows) and 200 receiving a 1.5 × PGF2α dose (PG1.5 group: 121 LE and 79 EF cows). The induced abortion rate was significantly lower (chi-square test; p < 0.0001) in the EF (34.6%) than LE cows (88%), and was also reduced (p = 0.001) in the EF PG1 group (28%) compared with the EF PG1.5 group (48.1%). High milk production (≥45 kg) was the only factor influencing the induced abortion rate in LE cows (odds ratio 0.2; p < 0.0001), whereas the odds ratio for induced abortion of PG1.5 cows was 2.3 (p = 0.005) in EF cows. In conclusion, an increased PGF2α dose had no effect on abortion induction during the late embryonic period and its rate was inversely associated with milk production. This higher PGF2α dose did, however, offer benefits during the early fetal period.