Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules

[eng] This work of thesis is organized into 8 different chapters: Chapter 1: introduces the nanoscale electrical properties of cells and their relevance in the different fields of science in order to establish a framework for the objectives of the project. Chapter 2: introduces the Scanning Probe Mi...

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Detalles Bibliográficos
Autor: Checa Nualart, Martí
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/151820
Acceso en línea:https://hdl.handle.net/2445/151820
http://hdl.handle.net/10803/668753
Access Level:acceso abierto
Palabra clave:Nanotecnologia
Electrònica en biologia
Nanotechnology
Electronics in biology
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spelling Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lulesCheca Nualart, MartíNanotecnologiaElectrònica en biologiaNanotechnologyElectronics in biology[eng] This work of thesis is organized into 8 different chapters: Chapter 1: introduces the nanoscale electrical properties of cells and their relevance in the different fields of science in order to establish a framework for the objectives of the project. Chapter 2: introduces the Scanning Probe Microscopy techniques, with a special interest in its electrical modes. It mainly focuses the interest on Electrostatic Force Microscopy as it is the technique used during the project. Motivation and objectives of the thesis: Once the introductory chapters have established a framework for the realization of the thesis, its motivation, and its main goals are exposed. Chapter 3: covers the theoretical modeling of electrostatic force measurements in electrolyte solutions for 1D geometry. Chapter 4: extends the theoretical modeling of electrostatic force measurements in electrolyte solutions to 3D realistic geometries, and their implications regarding EFM in liquid media are discussed. Chapter 5: presents and validates a new SPM technique called Scanning Dielectric Force Volume Microscopy (SDFVM) designed specially to deal with topographically complex and heterogeneous samples like cells. Chapter 6: exposes the application of SDFVM to obtain the first (to our knowledge) local dielectric constant map of a cell at the sub-cellular level. Chapter 7: uses the developed technique to obtain EFM images of different interesting systems in nanotechnology, showing the power of method by achieving nice images in a wide range of systems going from small nanowires to big eukaryotic cells. Chapter 8: presents the steps performedtowards implementing SDFVM into liquid environments, and some preliminary results for fixed and living eukaryotic cells in pyhsiological conditions. Then the conditions of the project and its futures perspectives are exposed. The references can be found at the end of the document.Universitat de BarcelonaGomila Lluch, GabrielUniversitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica2020info:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/151820http://hdl.handle.net/10803/668753Tesis Doctorals - Departament - Enginyeria Electrònica i Biomèdicareponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaEspañol(c) Checa, 2020info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1518202026-05-27T06:46:51Z
dc.title.none.fl_str_mv Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
title Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
spellingShingle Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
Checa Nualart, Martí
Nanotecnologia
Electrònica en biologia
Nanotechnology
Electronics in biology
title_short Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
title_full Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
title_fullStr Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
title_full_unstemmed Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
title_sort Una nova tècnica de microscòpia de forces atòmiques per a l'estudi de les propietats nanoelèctriques de les cèl·lules
dc.creator.none.fl_str_mv Checa Nualart, Martí
author Checa Nualart, Martí
author_facet Checa Nualart, Martí
author_role author
dc.contributor.none.fl_str_mv Gomila Lluch, Gabriel
Universitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica
dc.subject.none.fl_str_mv Nanotecnologia
Electrònica en biologia
Nanotechnology
Electronics in biology
topic Nanotecnologia
Electrònica en biologia
Nanotechnology
Electronics in biology
description [eng] This work of thesis is organized into 8 different chapters: Chapter 1: introduces the nanoscale electrical properties of cells and their relevance in the different fields of science in order to establish a framework for the objectives of the project. Chapter 2: introduces the Scanning Probe Microscopy techniques, with a special interest in its electrical modes. It mainly focuses the interest on Electrostatic Force Microscopy as it is the technique used during the project. Motivation and objectives of the thesis: Once the introductory chapters have established a framework for the realization of the thesis, its motivation, and its main goals are exposed. Chapter 3: covers the theoretical modeling of electrostatic force measurements in electrolyte solutions for 1D geometry. Chapter 4: extends the theoretical modeling of electrostatic force measurements in electrolyte solutions to 3D realistic geometries, and their implications regarding EFM in liquid media are discussed. Chapter 5: presents and validates a new SPM technique called Scanning Dielectric Force Volume Microscopy (SDFVM) designed specially to deal with topographically complex and heterogeneous samples like cells. Chapter 6: exposes the application of SDFVM to obtain the first (to our knowledge) local dielectric constant map of a cell at the sub-cellular level. Chapter 7: uses the developed technique to obtain EFM images of different interesting systems in nanotechnology, showing the power of method by achieving nice images in a wide range of systems going from small nanowires to big eukaryotic cells. Chapter 8: presents the steps performedtowards implementing SDFVM into liquid environments, and some preliminary results for fixed and living eukaryotic cells in pyhsiological conditions. Then the conditions of the project and its futures perspectives are exposed. The references can be found at the end of the document.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
info:eu-repo/semantics/publishedVersion
format doctoralThesis
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/151820
http://hdl.handle.net/10803/668753
url https://hdl.handle.net/2445/151820
http://hdl.handle.net/10803/668753
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.rights.none.fl_str_mv (c) Checa, 2020
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Checa, 2020
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universitat de Barcelona
publisher.none.fl_str_mv Universitat de Barcelona
dc.source.none.fl_str_mv Tesis Doctorals - Departament - Enginyeria Electrònica i Biomèdica
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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