Patient-Ventilator Synchronization During Non-invasive Ventilation

Background: Patient-ventilator synchronization during non-invasive ventilation (NIV) can be assessed by visual inspection of flow and pressure waveforms but it remains time consuming and there is a large inter-rater variability, even among expert physicians. ™ software developed by Breas Medical (Mö...

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Detalles Bibliográficos
Autores: Letellier, Christophe, Luján, Manel|||0000-0001-9033-7712, Arnal, Jean-Michel, Carlucci, Annalisa, Chatwin, Michelle, Ergan, Begum, Kampelmacher, Mike, Storre, Jan Hendrik, Hart, Nicholas, Gonzalez-Bermejo, Jesus, Nava, Stefano
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:252200
Acceso en línea:https://ddd.uab.cat/record/252200
https://dx.doi.org/urn:doi:10.3389/fmedt.2021.690442
Access Level:acceso abierto
Palabra clave:Non-invasive ventilation
Patient ventilator asynchrony
Chronic obstructive pulmonary disease
Ineffective triggering
Monitoring
Automatic scoring
Descripción
Sumario:Background: Patient-ventilator synchronization during non-invasive ventilation (NIV) can be assessed by visual inspection of flow and pressure waveforms but it remains time consuming and there is a large inter-rater variability, even among expert physicians. ™ software developed by Breas Medical (Mölnycke, Sweden) provides an automatic detection and scoring of patient-ventilator asynchrony to help physicians in their daily clinical practice. This study was designed to assess performance of the automatic scoring by the software using expert clinicians as a reference in patient with chronic respiratory failure receiving NIV. Methods: From nine patients, 20 min data sets were analyzed automatically by software and reviewed by nine expert physicians who were asked to score auto-triggering (AT), double-triggering (DT), and ineffective efforts (IE). The study procedure was similar to the one commonly used for validating the automatic sleep scoring technique. For each patient, the asynchrony index was computed by automatic scoring and each expert, respectively. Considering successively each expert scoring as a reference, sensitivity, specificity, positive predictive value (PPV), κ-coefficients, and agreement were calculated. Results: The asynchrony index assessed by was not significantly different from the one assessed by the experts (18.9 ± 17.7 vs. 12.8 ± 9.4, p = 0.19). When compared to an expert, the sensitivity and specificity provided by for DT, AT, and IE were significantly greater than those provided by an expert when compared to another expert. Conclusions: software is able to score asynchrony events within the inter-rater variability. When the breathing frequency is not too high (<24), it therefore provides a reliable assessment of patient-ventilator asynchrony; AT is over detected otherwise.