Parathyroid autotransplantation in thyroid surgery

BACKGROUND: Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of hyperplastic parathyroid tissue in patients with renal or hereditary hyperparat...

ver descrição completa

Detalhes bibliográficos
Autores: Sitges-Serra, Antonio, Lorente-Poch, Leyre, Sancho Insenser, Juan
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Recursos:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/35939
Acesso em linha:http://hdl.handle.net/10230/35939
http://dx.doi.org/10.1007/s00423-018-1654-5
Access Level:acceso abierto
Palavra-chave:Tiroide -- Malalties
Hypoparathyroidism
Parathyroid autotransplantation
Preservation
Thyroidectomy
id ES_9f83c4a5cdda3b1c0d8a4d0592012bc4
oai_identifier_str oai:repositori.upf.edu:10230/35939
network_acronym_str ES
network_name_str España
repository_id_str
spelling Parathyroid autotransplantation in thyroid surgerySitges-Serra, AntonioLorente-Poch, LeyreSancho Insenser, JuanTiroide -- MalaltiesHypoparathyroidismParathyroid autotransplantationPreservationThyroidectomyBACKGROUND: Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of hyperplastic parathyroid tissue in patients with renal or hereditary hyperparathyroidism did popularize the use of normal parathyroid tissue autografts during thyroidectomy to prevent permanent hypoparathyroidism. Proof of autograft function in this setting, however, is controversial. PURPOSE: This narrative review aims at reviewing critically the current status of parathyroid autotransplantation during total thyroidectomy. It is also meant to analyze from the historical, methodological, and clinical points of view the claimed benefit of normal parathyroid gland autotransplantation. A focus is placed on the prevention of permanent hypoparathyroidism by parathyroid autotransplantation. CONCLUSIONS: Liberal parathyroid autotransplantation was proposed in the mid 1970s but evidence of function is scarce. Proofs are accumulating that parathyroid autografts not only increase the rate of postoperative hypocalcemia, but may be also contribute to permanent hypoparathyroidism.Springer20182018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/35939http://dx.doi.org/10.1007/s00423-018-1654-5reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésLangenbeck's Archives of Surgery. 2018 May;403(3):309-15© Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s00423-018-1654-5.info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/359392026-06-12T07:21:37Z
dc.title.none.fl_str_mv Parathyroid autotransplantation in thyroid surgery
title Parathyroid autotransplantation in thyroid surgery
spellingShingle Parathyroid autotransplantation in thyroid surgery
Sitges-Serra, Antonio
Tiroide -- Malalties
Hypoparathyroidism
Parathyroid autotransplantation
Preservation
Thyroidectomy
title_short Parathyroid autotransplantation in thyroid surgery
title_full Parathyroid autotransplantation in thyroid surgery
title_fullStr Parathyroid autotransplantation in thyroid surgery
title_full_unstemmed Parathyroid autotransplantation in thyroid surgery
title_sort Parathyroid autotransplantation in thyroid surgery
dc.creator.none.fl_str_mv Sitges-Serra, Antonio
Lorente-Poch, Leyre
Sancho Insenser, Juan
author Sitges-Serra, Antonio
author_facet Sitges-Serra, Antonio
Lorente-Poch, Leyre
Sancho Insenser, Juan
author_role author
author2 Lorente-Poch, Leyre
Sancho Insenser, Juan
author2_role author
author
dc.subject.none.fl_str_mv Tiroide -- Malalties
Hypoparathyroidism
Parathyroid autotransplantation
Preservation
Thyroidectomy
topic Tiroide -- Malalties
Hypoparathyroidism
Parathyroid autotransplantation
Preservation
Thyroidectomy
description BACKGROUND: Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of hyperplastic parathyroid tissue in patients with renal or hereditary hyperparathyroidism did popularize the use of normal parathyroid tissue autografts during thyroidectomy to prevent permanent hypoparathyroidism. Proof of autograft function in this setting, however, is controversial. PURPOSE: This narrative review aims at reviewing critically the current status of parathyroid autotransplantation during total thyroidectomy. It is also meant to analyze from the historical, methodological, and clinical points of view the claimed benefit of normal parathyroid gland autotransplantation. A focus is placed on the prevention of permanent hypoparathyroidism by parathyroid autotransplantation. CONCLUSIONS: Liberal parathyroid autotransplantation was proposed in the mid 1970s but evidence of function is scarce. Proofs are accumulating that parathyroid autografts not only increase the rate of postoperative hypocalcemia, but may be also contribute to permanent hypoparathyroidism.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/35939
http://dx.doi.org/10.1007/s00423-018-1654-5
url http://hdl.handle.net/10230/35939
http://dx.doi.org/10.1007/s00423-018-1654-5
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Langenbeck's Archives of Surgery. 2018 May;403(3):309-15
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869414934938386432
score 15,81155

Registos relacionados