Hepatitis E as a trigger for acute-on-chronic liver failure

Acute hepatitis E virus (HEV) infection is typically self-limiting and has a favourable prognosis. However, certain populations such as patients with pre-existing chronic liver disease may experience severe manifestations, including progression to acute-on-chronic liver failure (ACLF). Among viral h...

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Detalles Bibliográficos
Autores: Buti, Maria|||0000-0002-0732-3078, Ruiz Cobo, Juan Carlos|||0000-0003-2239-4939, Esteban, Rafael|||0000-0001-5280-392X, Riveiro Barciela, Mar|||0000-0001-9309-2052
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:326093
Acceso en línea:https://ddd.uab.cat/record/326093
https://dx.doi.org/urn:doi:10.3350/cmh.2024.0758
Access Level:acceso abierto
Palabra clave:Hepatitis E
Acute on chronic liver failure
Liver cirrhosis
Ribavirin
Vaccination
Descripción
Sumario:Acute hepatitis E virus (HEV) infection is typically self-limiting and has a favourable prognosis. However, certain populations such as patients with pre-existing chronic liver disease may experience severe manifestations, including progression to acute-on-chronic liver failure (ACLF). Among viral hepatitis types, hepatitis A, E, and B are major causes of ACLF. Active screening and early diagnosis of HEV infection in patients with cirrhosis, especially those who develop ACLF, can improve management and enable timely antiviral therapy. Preventive measures, including HEV vaccination for high-risk groups, could reduce the morbidity and mortality associated with hepatitis E.